Results 151 to 160 of about 2,996,820 (336)
ABSTRACT Objective Neurodegeneration with brain iron accumulation (NBIA) comprises rare genetic disorders characterized by predominantly extrapyramidal symptoms and iron deposition in the basal ganglia. Conventional magnetic resonance imaging (MRI) detects qualitative changes but cannot accurately quantify iron accumulation. Quantitative susceptibility
Özge Uygun+19 more
wiley +1 more source
Joint Analysis of Longitudinal Data Comprising Repeated Measures and Times to Events [PDF]
Jane Xu, Scott L. Zeger
openalex +1 more source
Practice Recommendations for Genetic Testing of Ataxias
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan+7 more
wiley +1 more source
Factors affecting blood sugar changes in diabetic patients using a three-level model in analysis of longitudinal data [PDF]
Background: Diabetes, a currently threatening disease, has severe consequences for individuals’ health conditions. The present study aimed to investigate the factors affecting the changes in the longitudinal outcome of blood sugar using a three-level ...
Tahereh Rohani+5 more
doaj
Joint modelling of longitudinal measurements and event time data
Robert K. Henderson
openalex +1 more source
Causal Inference for Complex Longitudinal Data: The Continuous Case [PDF]
Richard D. Gill, James M. Robins
openalex +1 more source
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski+13 more
wiley +1 more source
Analysis of Longitudinal Data from Progeny Tests: Some Multivariate Approaches [PDF]
Luis A. Apiolaza, Dorian J. Garrick
openalex +1 more source
Genetic Modifiers of Parkinson's Disease: A Case–Control Study
ABSTRACT Objective To examine the associations of LRRK2 p.G2019S, GBA1 p.N409S, polygenic risk scores (PRS), and APOE E4 on PD penetrance, risk, and symptoms. Methods We conducted a US‐based observational case–control study using data from the 23andMe Inc. and Fox Insight Genetic Substudy (FIGS) databases.
Matthew J. Kmiecik+15 more
wiley +1 more source
The Error Structure of Earnings: An Analysis on Italian Longitudinal Data [PDF]
Margherita Borella
openalex +1 more source