Results 91 to 100 of about 1,824,593 (305)

Depression and socio-economic risk factors: 7-year longitudinal population study [PDF]

British Journal of Psychiatry, 2007
BackgroundLow socio-economic status is associated with a higher prevalence of depression, but it is not yet known whether change in socio-economic status leads to a change in rates of depression.AimsTo assess whether longitudinal change in socio-economic factors affects change of depression level.MethodIn a prospective cohort study using the annual ...
Lorant, V., Croux, C., Weich, S., Deliege, D., Mackenbach, J., Ansseau, Marc   +5 more
openaire   +3 more sources

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

Molecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié, Umberto Malapelle, Catherine Alix‐Panabières, Claus Lindbjerg Andersen, Sandra Chlebowski, Vivien Lake, Caroline Lacoux, Virginie Lespinet‐Fabre, Olivier Bordone, Simon Heeke, Christophe Bontoux, Ellen Heitzer, Klaus Pantel, Paul Hofman   +13 more
wiley   +1 more source

Genetic impacts on DNA methylation help elucidate regulatory genomic processes

Genome Biology, 2023
Background Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways that underlie gene regulation and disease risk. Results We report heritability and methylation quantitative trait locus (meQTL) analysis at 724,499 CpGs ...
Sergio Villicaña, Juan Castillo-Fernandez, Eilis Hannon, Colette Christiansen, Pei-Chien Tsai, Jane Maddock, Diana Kuh, Matthew Suderman, Christine Power, Caroline Relton, George Ploubidis, Andrew Wong, Rebecca Hardy, Alissa Goodman, Ken K. Ong, Jordana T. Bell   +15 more
doaj   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Arterial stiffness and multiple organ damage: a longitudinal study in population [PDF]

Aging Clinical and Experimental Research, 2019
Previous cross-sectional observation identified arterial aging, indexed as pulse-wave velocity (PWV), as a key determinant of the simultaneous multiple organ damage (heart, carotid artery, and kidney). The aim of the present cohort study is to investigate trajectories of repeated measures of PWV and traditional CV risk factors in subjects who ...
Scuteri A., Morrell C. H., Alunni Fegatelli D., Fiorillo E., Delitala A., Orru' M., Marongiu M., Schlessinger D., Cucca F.   +8 more
openaire   +5 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Measurement error in long-term retrospective recall surveys of earnings [PDF]

, 2007
Several recent studies in labour and population economics use retrospective surveys to substitute for the high cost and limited availability of longitudinal survey data.
Gibson, John, Kim, Bonggeun
core   +1 more source

Understanding Longitudinal Population Study Data and the Law

International Journal of Population Data Science
BackgroundUK Longitudinal Linkage Collaboration (UK LLC) is the national Trusted Research Environment for the UK's longitudinal studies. The need for a clear way to communicate Longitudinal Population Study (LPS) participants’ rights was identified through public contributor consultations.
Kirsteen Campbell, Rebecca Whitehorn, Sarah Chave, Michael Gregg, Mhairi Docherty, Rosie Hill, Emma Turner, Katharine Evans, Jacqui Oakley, Robin Flaig, Andy Boyd   +10 more
openaire   +2 more sources

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

Relation of Insulin Resistance to Longitudinal Changes in Left Ventricular Structure and Function in a General Population

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018
BackgroundPopulation data on the longitudinal changes of left ventricular (LV) structure and function in relation to insulin resistance are sparse. Therefore, we assessed in a general population whether hyperinsulinemia predicts longitudinal changes in ...
Nicholas Cauwenberghs, Judita Knez, Lutgarde Thijs, Francois Haddad, Thomas Vanassche, Wen‐Yi Yang, Fang‐Fei Wei, Jan A. Staessen, Tatiana Kuznetsova   +8 more
doaj   +1 more source