Results 91 to 100 of about 1,836,276 (227)

The individual, place, and wellbeing – a network analysis

BMC Public Health, 2021
Background Previous research has examined individual-level and place characteristics as correlates of subjective wellbeing, with many studies concluding that individual factors (e.g. health, finances) are more strongly related to wellbeing. However, this
Eoin McElroy, Mathew Ashton, Anne Marie Bagnall, Terence Comerford, Mick McKeown, Praveetha Patalay, Andy Pennington, Jane South, Tim Wilson, Rhiannon Corcoran   +9 more
doaj   +1 more source

Systematic review and evidence appraisal of objectively assessed longitudinal changes in moderate-to-vigorous physical activity among children and adolescents (2-18 years old) [PDF]

, 2016
The aim of this study was to systematically review accelerometer based longitudinal studies which have quantified year to year changes in moderate-to-vigorous physical activity (MVPA) among the general paediatric population in the absence of any ...
Farooq, Mohammed Abdul Aziz, Hughes, Adrienne, Knowles, Ann-Marie, Martin, Anne, Reilly, John, Wilson, Mathew   +5 more
core  

Depression and socio-economic risk factors: 7-year longitudinal population study [PDF]

British Journal of Psychiatry, 2007
BackgroundLow socio-economic status is associated with a higher prevalence of depression, but it is not yet known whether change in socio-economic status leads to a change in rates of depression.AimsTo assess whether longitudinal change in socio-economic factors affects change of depression level.MethodIn a prospective cohort study using the annual ...
Lorant, V., Croux, C., Weich, S., Deliege, D., Mackenbach, J., Ansseau, Marc   +5 more
openaire   +3 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Sexual orientation and symptoms of common mental disorder or low wellbeing: combined meta-analysis of 12 UK population health surveys [PDF]

, 2016
Background Previous studies have indicated increased risk of mental disorder symptoms, suicide and substance misuse in lesbian, gay and bisexual (LGB) adults, compared to heterosexual adults.
A Chakraborty, B Everett, B Needham, D Chae, DJ Lick, G Knies, G Meckler, Gareth Hagger-Johnson, H Williams, Health and Social Care Information Centre, Health and Social Care Information Centre, Health and Social Care Information Centre, I Meyer, I Meyer, J Almeida, J Brazier, J Elliott, J-W Weenink, Joanna Semlyen, Justin Varney, K McLaughlin, L Durso, L Lindley, L Wichstrøm, M Hatzenbuehler, M King, M Rosario, M Rosario, Michael King, Office of National Statistics, P Kind, P Serrano-Aguilar, Public Health England, T Debray, T Sandfort   +34 more
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Genetic impacts on DNA methylation help elucidate regulatory genomic processes

Genome Biology, 2023
Background Pinpointing genetic impacts on DNA methylation can improve our understanding of pathways that underlie gene regulation and disease risk. Results We report heritability and methylation quantitative trait locus (meQTL) analysis at 724,499 CpGs ...
Sergio Villicaña, Juan Castillo-Fernandez, Eilis Hannon, Colette Christiansen, Pei-Chien Tsai, Jane Maddock, Diana Kuh, Matthew Suderman, Christine Power, Caroline Relton, George Ploubidis, Andrew Wong, Rebecca Hardy, Alissa Goodman, Ken K. Ong, Jordana T. Bell   +15 more
doaj   +1 more source

Arterial stiffness and multiple organ damage: a longitudinal study in population [PDF]

Aging Clinical and Experimental Research, 2019
Previous cross-sectional observation identified arterial aging, indexed as pulse-wave velocity (PWV), as a key determinant of the simultaneous multiple organ damage (heart, carotid artery, and kidney). The aim of the present cohort study is to investigate trajectories of repeated measures of PWV and traditional CV risk factors in subjects who ...
Scuteri A., Morrell C. H., Alunni Fegatelli D., Fiorillo E., Delitala A., Orru' M., Marongiu M., Schlessinger D., Cucca F.   +8 more
openaire   +5 more sources

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Understanding Longitudinal Population Study Data and the Law

International Journal of Population Data Science
BackgroundUK Longitudinal Linkage Collaboration (UK LLC) is the national Trusted Research Environment for the UK's longitudinal studies. The need for a clear way to communicate Longitudinal Population Study (LPS) participants’ rights was identified through public contributor consultations.
Kirsteen Campbell, Rebecca Whitehorn, Sarah Chave, Michael Gregg, Mhairi Docherty, Rosie Hill, Emma Turner, Katharine Evans, Jacqui Oakley, Robin Flaig, Andy Boyd   +10 more
openaire   +2 more sources