Results 61 to 70 of about 17,846,830 (303)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Epidemiology of insomnia: a longitudinal study in a UK population. [PDF]
Sleep, 2007 To investigate the incidence, persistence, and consequences of insomnia and their associations with psychological health and pain.A population based, longitudinal, cohort study using postal questionnaires at baseline and 12-month follow-up. Sleep problems in the past month were assessed using 4 questions: insomnia was defined as having at least 1 of ...
Hannah, Morphy +4 more
openaire +3 more sources
The human gut microbiome across the life course
FEBS Letters, EarlyView.Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Scientific ReportsAir pollution is associated with health in childhood. However, there is limited evidence on sensitive periods during the first 18 years of life. Data were drawn from the Millennium Cohort Study, a large and nationally representative cohort born in 2000 ...
Gergő Baranyi +4 more
doaj +1 more source
Longitudinal population-based studies of affective disorders: Where to from here?
BMC Psychiatry, 2008 Background Longitudinal, population-based, research is important if we are to better characterize the lifetime patterns and determinants of affective disorders.
Beard John R, Galea Sandro, Vlahov David
doaj +1 more source
Components of regional population growth, 1986-2001 [PDF]
, 2004 The vitality of a region is frequently assessed by looking at its population growth pattern. This is seen as being linked to its economic and social vibrancy.
Pool, Ian +2 more
core
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
SSM - Mental Health, 2021 Objective: Exposure to adverse childhood experiences (ACEs) is associated with a broad range of mental health-related outcomes. Previous studies tended to use retrospectively reported ACEs, measure mental health outcomes at a one time point in adulthood ...
Dawid Gondek +2 more
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
JCPP Advances, 2023 Introduction Longitudinal studies of child mental disorders in the general population (herein study) investigate trends in prevalence, incidence, risk/protective factors, and sequelae for disorders.
Theodora Bogdan +7 more
doaj +1 more source