Results 61 to 70 of about 229,943 (347)

Decreased Serum 5‐HT: Clinical Correlates and Regulatory Role in NMJ of MG

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although 5‐Hydroxytryptamine (5‐HT) indirectly stimulates muscle contraction and participates in regulating Acetylcholine receptor (AChR) cluster homeostasis in cellular, animal, and clinical studies, evidence regarding its potential to modulate muscle contraction in myasthenia gravis (MG) remains limited.
Xinru Shen, Jing Zhang, Xinyue Zhou, Xiaoxiao Yu, Haodong Shang, Shufan Chen, Lulu Zhen, Jinru Wu, Guanlian Hu, Xiaoyan Zhu, Zhan Sun, Yiren Wang, Jiahui Wang, Jie Lv, Xue Zhao, Yingna Zhang, Wei Guo, Ying Peng, Feng Gao   +18 more
wiley   +1 more source

Analysis of Static Aeroelastic Characteristics of Distributed Propulsion Wing

Aerospace
The static aeroelastic characteristics of the distributed propulsion wing (DPW) were studied using the CFD/CSD loose coupling method in this study. The momentum source method of the Reynolds-averaged Navier–Stokes equation based on the k-ω SST turbulence
Junlei Sun, Zhou Zhou, Tserendondog Tengis, Huailiang Fang   +3 more
doaj   +1 more source

Transonic static aeroelastic and longitudinal aerodynamic characteristics of a low-aspect-ratio swept wing

AIP Advances, 2019
Based on the CFD/CSD coupling method, the transonic static aeroelastic characteristics of the low-aspect-ratio swept wing was studied by numerical simulation. The Navier-Stokes equation was used as the fluid computational control equations.
Junli Wang
doaj   +1 more source

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Longitudinal aerodynamic parameters of the Kestrel aircraft (XV-6A) extracted from flight data [PDF]

Flight-test data have been used to extract the longitudinal aerodynamic parameters of a vectored-thrust aircraft. The results show that deflecting the thrust past 15 has an effect on the pitching-moment derivatives and tends to reduce the static ...
Suit, W. T., Williams, J. L.
core   +1 more source

The Relationship Between Inflammation and Central Nervous System in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Aim Multiple sclerosis is an autoimmune demyelination disease that is seen especially in the young population and has a progressive course, causing motor, sensory, and cognitive deficits. In the literature, the pathogenesis of MS disease and the interconnection between the immune and central nervous system in the disease have not been fully ...
Gamze Ansen, Ali Behram Salar, Abdulkadir Ermis, Erkingul Birday, Lutfu Hanoglu, Bayram Ufuk Sakul   +5 more
wiley   +1 more source

Assessment of Propulsion Patterns for Hybrid Wing Configuration Aircraft with Embedded Propellers

Aerospace
This study employs computational fluid dynamics (CFD) to investigate the aerodynamic performance and static stability of hybrid wing aircraft, considering the interference of counter-rotating embedded propellers. Extensive numerical verification has been
Xiaolu Wang, Changning Chen, Zhihao Jiao, Jiahao Li, Ke Zhao   +4 more
doaj   +1 more source

Static and dynamic stability analysis of the space shuttle vehicle-orbiter [PDF]

The longitudinal static and dynamic stability of a Space Shuttle Vehicle-Orbiter (SSV Orbiter) model is analyzed using the FLEXSTAB computer program. Nonlinear effects are accounted for by application of a correction technique in the FLEXSTAB system; the
Cavin, R. K., Chyu, W. J., Erickson, L. L.   +2 more
core   +1 more source

Development of a new running gear for the Spectrum intermodal vehicle [PDF]

, 2016
The European Union (EU) Seventh Framework Programme (FP7) project Spectrum [12] set out to develop a freight vehicle which would facilitate the exploitation of the low density, high value (LDHV) goods market.
Bezin, Yann, Crosbee, David, Kaushal, Aniruddha, Molyneux-Berry, Paul, Shackleton, Philip   +4 more
core   +1 more source

Use of Symptomatic Drug Treatment for Fatigue in Multiple Sclerosis and Patterns of Work Loss

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe the use of central stimulants and amantadine for fatigue in MS and evaluate a potential association with reduced work loss in people with MS. Methods We conducted a nationwide, matched, register‐based cohort study in Sweden (2006 to 2023) using national registers with prospective data collection.
Simon Englund, Johan Reutfors, Thomas Frisell, Fredrik Piehl   +3 more
wiley   +1 more source