Results 51 to 60 of about 2,462,283 (306)

Examples of longitudinal, circumferential and radial myocardial strain and strain rate profiles in different species studied.

, 2012
Examples of longitudinal, circumferential and radial myocardial strain and strain rate profiles in different species studied.
Marc S. Penn (154830), Youhua Zhang (154831), Yuanna Cheng (154832), Kenya Kusunose (154829), Thomas H. Marwick (154834), Zoran B. Popović (154836), James D. Thomas (154833)   +6 more
core   +1 more source

The learning curve for competency in right ventricular longitudinal strain analysis

, 2020
The application of myocardial strain by two-dimensional speckle-tracking to quantify right ventricular (RV) function has recently been endorsed by the American Society of Echocardiography/European Association of Cardiovascular Imaging Joint Industry Task
Hlaing, Su, Chamberlain, Robert, Hotham, Ian, Scalia, Gregory M., Page-Taylor, Estelle, Wee, Yong, Chan, Jonathan, Scalia, Gregory M, Lee, Abbie, Sabapathy, Surendran   +9 more
core   +1 more source

Longitudinal Speckle Tracking Strain Abnormalities in Chagas Disease: A Systematic Review and Meta-Analysis. [PDF]

, 2022
BACKGROUND Chronic Chagas cardiomyopathy (CCM) is ranked among heart failure etiologies with the highest mortality rates. CCM is characterized by alterations in left ventricular function with a typical and unique pattern of myocardial involvement ...
Muka, Taulant, Sergio Alejandro Gómez-Ochoa, Taulant Muka, Rojas, Lyda Z, Jorge Largo, Echeverría, Luis E, Lyda Z. Rojas, Hernández-Vargas, Juliana Alexandra, Gómez-Ochoa, Sergio Alejandro, Largo, Jorge, Juliana Alexandra Hernández-Vargas, Luis E. Echeverría   +11 more
core   +2 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Soluble Flt1 levels are associated with cardiac dysfunction in Black women with and without severe preeclampsia

Hypertension in Pregnancy, 2021
Background: We evaluate soluble fms-like tyrosine kinase-1 (sFlt-1) levels and cardiac function during pregnancy and postpartum among Black women with and without preeclampsia.
Lisa Levine, Zolt Arany, Adina Kern-Goldberger, Nathanael Koelper, Jennifer Lewey, Mary D. Sammel, Michal A. Elovitz, Bonnie Ky   +7 more
doaj   +1 more source

The association between left ventricular global longitudinal strain, renal impairment and all-cause mortality

, 2014
Left ventricular (LV) global longitudinal strain (GLS) may identify subclinical myocardial dysfunction in patients with aortic stenosis (AS). The aims of the present retrospective single centre study were to determine the independent prognostic value of ...
Krishnasamy, Rathika, Leano, R, Haluska, BA, Hawley, Carmel M., Stanton, T, Leano, Rodel, Pascoe, EM, Isbel, Nicole M., Haluska, Brian A., Pascoe, Elaine M., Hawley, CM, Krishnasamy, R, Stanton, Tony, Isbel, NM   +13 more
core   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Role of speckle tracking echocardiography in patients with myocardial infarction

Patologìâ, 2021
All over the world cardiovascular diseases are one of the main reason of morbidity and mortality in the structure of non-communicable diseases, and myocardial infarction has a leading role.
A. V. Kobets, M. P. Kopytsia, N. V. Tytarenko, Yu. V. Rodionova   +3 more
doaj   +1 more source