Results 161 to 170 of about 357,338 (295)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Medial meniscus posterior root tear with concomitant focal cartilage lesion may be successfully treated with pullout repair combined with additional bone marrow stimulation. [PDF]

open access: yesAsia Pac J Sports Med Arthrosc Rehabil Technol
Okazaki Y   +8 more
europepmc   +1 more source

Consistent Look-up Table interpolation method for real-gas flow simulations

open access: yes, 2014
Nowadays the reliable modeling of real fluid flows is of paramount importance in many industrial applications, especially in the energy field with the growing diffusion of Organic Rankine Cycles, supercritical CO2 compressors, and advanced refrigeration ...
M. Pini   +3 more
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

A Method to Parallelize Lookup Table (LUT) Method for Inverse Halftoning and its Hardware Implementation

open access: yes, 2008
Lookup table (LUT) method for inverse halftoning is computation less, fast and also yields goods results. This paper introduces a method to parallelize the LUT method of inverse halftoning. This is accomplished by dividing the single Look-Up Table of LUT
Sadiq M. Sait, Umair F. Siddiqi
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

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