Results 91 to 100 of about 1,233,327 (309)

Nanoscale Spatial Organization of ARC High‐ and Low‐Order Assemblies at Excitatory Synapses

Advanced Science, EarlyView.
ARC (Activity‐Regulated Cytoskeleton‐Associated protein) mediates synaptic plasticity by forming nanoscale assemblies in neurons. Using super‐resolution microscopy and time‐resolved anisotropy with targeted tagging, the study reveals low‐order ARC assemblies at synapses colocalizing with AMPARs, semi‐circular structures at endocytic zones, and 60–80 nm
Martina Damenti, Giovanna Coceano, Mariline Mendes Silva, Jonatan Alvelid, Chiara Sgattoni, Andrea Volpato, Lea Rems, Luciano A. Masullo, Eduard M. Unterauer, Rafal Kowalewski, Lucie Delemotte, Erdinc Sezgin, Ralf Jungmann, Ilaria Testa   +13 more
wiley   +1 more source

Scotland's looked after children: best educated in class, or do they need a 'hole in the wall'?

Scottish Journal of Residential Child Care, 2018
How can looked after children with special educational needs be supported outside the school day? Research suggests a significantly high proportion of looked after children have special educational needs.
Paul Lee Alan
doaj   +1 more source

Celebrating Success: What Helps Looked After Children Succeed [PDF]

, 2006
The aim of this study was to understand from people who have experienced being looked after, what helped them become and feel successful. We wanted to listen to those who had gone on to experience success in their lives, and to find out what they felt ...
Aldgate, Jane, Happer, Helen, McCreadie, Joanna   +2 more
core  

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

Nanomedicine Meets Immunotherapy: Advancing Adoptive Cell Therapy with Nanoparticles in the Treatment of Cancer with Sustainability Perspectives

Advanced Science, EarlyView.
This review surveys nanoparticle‐based strategies to enhance adoptive cell therapy, particularly CAR‐T cell approaches, in solid tumor treatment. It describes how nanoparticles can improve tumor immunogenicity and T‐cell infiltration while reducing toxicity, and how they enable in vivo CAR‐T cell generation.
Erica Frostegård, Tatiana Bobrova, Amalie Leinebø, Thibault Leray, Shayamita Ghosh, Lorena García‐Hevia, Chiara Puccinelli, Lorenzo Riccio, Jacopo Sorani, Davide Bonifazi, Julien Caumartin, Emmanuel Donnadieu, Florence Gazeau, Roland Hischier, Else Marit Inderberg, Mónica L. Fanarraga, Maria Loustau, Bernd Nowack, Sébastien Wälchli, Cécilia Ménard‐Moyon   +19 more
wiley   +1 more source

The University of Strathclyde summer experience: the impact of a widening access residential summer programme for children in care

Scottish Journal of Residential Child Care, 2013
The Innovative Routes to Learning (IRL) unit at the University of Strathclyde ran a three-day on-campus residential programme for children from a looked after (care) background from three Glasgow City Council schools during summer 2013, designed to build
Iain Mitchell
doaj   +1 more source

Prioritising Sibling Relationships for Looked After Children [PDF]

, 2018
This is a complex area, involving several different legal processes, with associated legislation and guidance. Overall, looked after children have few enforceable rights at present in law in relation to placement and contact with siblings.
Jones, Christine, Jones, Fiona
core  

Sport and physical activity in the lives of looked-after children: a ‘hidden group’ in research, policy and practice [PDF]

, 2014
Looked-after children are arguably one of the most disadvantaged groups in society and constitute a ‘hidden group’ in relation to sport and physical activity research, policy and practice.
Armour K., Australian Institute of Health and Welfare, Bourdieu P., Bourdieu P., Bourdieu P., Broad B., Burrows L., Child Welfare Information Gateway, Clark A., Deacon S. A., Department for Children, Schools and Families, Department for Education (DfE), Department for Education and Skills (DfES), Fitzgerald H., Gay J., James A., Munro E., Sandford R., Scott J., Thomas Quarmby   +19 more
core   +1 more source

Stable Diffusion Models Reveal a Persisting Human–AI Gap in Visual Creativity

Advanced Science, EarlyView.
This study examines visual creativity in humans and generative AI using the TCIA framework. Human artists outperform AI overall, yet structured human guidance substantially improves AI outputs and evaluations. Findings reveal that alignment with human creativity depends critically on contextual framing, highlighting both the promise and current ...
Silvia Rondini, Claudia Alvarez‐Martin, Paula Angermair‐Barkai, Olivier Penacchio, Marc Paz, Matthew Pelowski, Dan Dediu, Antoni Rodriguez‐Fornells, Xim Cerda‐Company   +8 more
wiley   +1 more source

Hard to teach, hard to reach, hard to justify: the challenge of participatory research with vulnerable young people

Educational Futures, 2011
The poor outcomes for looked after children (LAC) are well-documented: for example, a young person from a care background is 10 times more likely to be given a statement of special education need (SEN) than their peers (DCSF, 2009).
Catherine Lamond
doaj