Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz +9 more
wiley +1 more source
Celtiberian metrology and its romanization
Celtiberian metrology has scarcely been investigated until now, with the exception of coin weights. On the basis of measurements of pre-Roman mud bricks, a Celtiberian foot of 24 cm is proposed.
Leonard A. CURCHIN
doaj
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
This paper has provided an overview over the Viking Age burials containing textile- and cooking equipment, such as spindlewhorls, woolcombs, weaver`s baton, frying pans and loom weights in combination with weapons.
Lillian Time
doaj +1 more source
Rinvenimenti di pesi da telaio in edifici rustici: il caso di Villadose (Rovigo) [PDF]
The excavations by the “Università degli Studi”, Verona, under the scientific guidance of Prof. Giuliana M. Facchini, have brought to light a small room that is believed to have been used for the treatment of wool, given the nature of the loom weights ...
Collarin, B.C., Facchini, G.
core
The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley +1 more source
Mechanical properties of wool and cotton yarns used in twenty-first century tapestry: preparing for the future by understanding the present [PDF]
The conservation of historic tapestries is a complex and highly skilled task. Tapestries now being woven will need conservation in years to come. Can we, by understanding the properties of these contemporary works, assist the conservators of the future ...
Flowers, Thomas Hugh +2 more
core +1 more source
Chronological and Spatial Distribution of Skeletal Muscle Fat Replacement in FHL1‐Related Myopathies
ABSTRACT Objectives Variants in the FHL1 gene cause FHL1‐related myopathies (FHL1‐RMs), a group of neuromuscular disorders with diverse clinical presentations. This study aimed to comprehensively characterize the spatial and temporal patterns of skeletal muscle fat replacement throughout the whole body in FHL1‐RMs, to examine disease progression over ...
Rui Shimazaki +8 more
wiley +1 more source
Higher Efficiency In Prediction Of TIBO Activity By Evolutionary Neural Network [PDF]
The treatment of acquired immunodeficiency syndrome (AIDS) is a challenging medical problem. TIBO is a nonnucleoside reverse transcriptase inhibitor, which binds non-competitively to the hydrophobic pocket on the p66 subunit of RT enzyme.
Abhik Seal
core +1 more source
Producing Goods, Shaping People: The Materiality of Crafting
The study of craft production has a long and venerable history in archaeological research on ancient societies. In this chapter, I consider the crafting of useful and desired things from a materiality perspective by looking at the interactions between ...
Hendon, Julia A.
core +1 more source

