Model Checking Software via Abstraction of Loop Transitions [PDF]
, 2003 Natasha Sharygina, James C. Browne
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FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
A feedforward loop of NLRC5 (de)ubiquitination keeps IKK–NF-κB in check [PDF]
, 2015 Yinling Hu
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The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential
Aging and Cancer, EarlyView.As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley +1 more source
Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon +12 more
wiley +1 more source
From Checking to Sensemaking: A Caregiver-in-the-Loop Framework for AI-Assisted Task Verification in Dementia Care [PDF]
Joy Lai +4 more
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Checking the transverse Ward–Takahashi relation at one-loop order in four dimensions [PDF]
, 2006 M. R. Pennington, Richard Williams
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Efficient Loop Conditions for Bounded Model Checking Hyperproperties [PDF]
, 2023 Tzu-Han Hsu +3 more
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Accelerated Progression of Gait Impairment in Parkinson's Disease and REM Sleep Without Atonia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective People with Parkinson's disease (PD) and rapid eye movement (REM) sleep without atonia (RSWA) often have more severe gait disturbances compared to PD without RSWA. The association between the presence and expression of RSWA and the rate of progression of gait impairment in PD is unknown.
Sommer L. Amundsen‐Huffmaster +11 more
wiley +1 more source
Flight control systems development and flight test experience with the HiMAT research vehicles [PDF]
Two highly maneuverable aircraft technology (HiMAT) remotely piloted vehicles were flown a total of 26 flights. These subscale vehicles were of advanced aerodynamic configuration with advanced technology concepts such as composite and metallic structures,
Earls, Michael R., Kempel, Robert W.
core +1 more source