Results 51 to 60 of about 1,349,598 (293)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Banded versus Single-sided bonded space maintainers: A Comparative Study

open access: yesIndian Journal of Dental Sciences, 2018
Background: The present study is conducted to evaluate and compare the clinical performance of conventional band and loop space maintainer and fiber reinforced composite resin (FRCR) space maintainers.
Sudhir Mittal   +5 more
doaj   +1 more source

On the effective action for scalars in a general manifold to any loop order

open access: yesPhysics Letters B, 2023
Functional methods and a derivative expansion are employed for laying out a procedure to compute the effective action to any loop order, for scalar fields parametrising an arbitrary Riemannian manifold, while maintaining explicit field-space covariance ...
Rodrigo Alonso, Mia West
doaj   +1 more source

L-infinity spaces and derived loop spaces

open access: yes, 2014
We develop further the approach to derived differential geometry introduced in Costello's work on the Witten genus. In particular, we introduce several new examples of L-infinity spaces, discuss vector bundles and shifted symplectic structures on L-infinity spaces, and examine in some detail the example of derived loop spaces.
Grady, Ryan, Gwilliam, Owen
openaire   +3 more sources

Finite loop spaces are manifolds

open access: yesActa Mathematica, 2004
The purpose of this work is to show the following result: Theorem: Let \(B\) be a CW-complex and denote by \(X\) the loops on \(B\), \(\Omega B\). If \(H_*(X)=\bigoplus _i H_i(X)\) is a finitely generated abelian group, then \(X\) is homotopy equivalent to a compact, smooth parallelizable manifold.
Bauer, T.   +3 more
openaire   +3 more sources

On loop spaces of configuration spaces [PDF]

open access: yesTransactions of the American Mathematical Society, 2002
This article gives an analysis of topological and homological properties for loop spaces of configuration spaces. The main topological results are given by certain choices of product decompositions of these spaces, as well as “twistings" between the factors.
Cohen, F. R., Gitler, S.
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Numerical integration of loop integrals through local cancellation of threshold singularities

open access: yesJournal of High Energy Physics, 2022
We propose a new approach that allows for the separate numerical calculation of the real and imaginary parts of finite loop integrals. We find that at one-loop the real part is given by the Loop-Tree Duality integral supplemented with suitable ...
D. Kermanschah
doaj   +1 more source

Quantization of Reissner-Nordstr\"{o}m Black Holes and Their Non-Singular Quantum Behavior

open access: yes, 2012
Quantization of different regions of the Reissner-Nordstr\"{o}m space time (charged black hole) is done in the framework of loop quantum gravity. The geometry of Reissner-Nordstr\"{o}m space-time is expressed in terms of Ashtekar variables which form the
Heydari, Hoshang   +1 more
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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