Results 71 to 80 of about 169,216 (302)
Journal of Industrial TextilesThe durability of terry fabrics largely depends on the fixation strength of pile loops. However, existing standard test methods such as BS EN 15598 and GOST 23351-78 measure the combined resistance of multiple loops and cannot isolate the structural ...
Dildora Mamadalieva +8 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Adaptive Impedance-Conditioned Phase-Locked Loop for the VSC Converter Connected to Weak Grid
Energies, 2021 In this paper, an adaptive version of the impedance-conditioned phase-locked loop (IC-PLL), namely the adaptive IC-PLL (AIC-PLL), is proposed. The IC-PLL has recently been proposed to address the issue of synchronisation with a weak AC grid by ...
Mostafa A. Hamood +2 more
doaj +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Exotic gravity theory in loop space [PDF]
An exotic linearised theory of superconformal gravity in D = 6, (4,0) superspace, proposed by C. Hull, is discussed in loop space with focus on its bosonic sector.
Lindström, U., Howe, P. S.
core +3 more sources
Open-loop and Closed-loop control of a Flow over a Cluster of Three Cylinders with Variable Spin Rate in Equilateral Triangular Arrangement [PDF]
, 2020 The control of the flow over a cluster of three rotating cylinders arranged in a triangular configuration (pinball-configuration) is simulated using 2D URANS.
Zhong, Xiao Peng
core +1 more source
eXPRESS Polymer Letters, 2007 The adhesion properties, i. e. viscosity, tack and peel strength of styrene-butadiene rubber (SBR)/Standard Malaysian Rubber (SMR L)-based pressure-sensitive adhesive was studied using phenol formaldehyde resin as the tackifying resin.
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Fabricação e caracterização de elementos porosos para bombas capilares / [PDF]
, 1998 Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro ...
Reimbrecht, Eduardo Gonçalves
core