Results 31 to 40 of about 332,988 (266)

Regulative Loops, Step Loops and Task Loops [PDF]

open access: yesInternational Journal of Artificial Intelligence in Education, 2015
This commentary suggests a generalization of the conception of the behavior of tutoring systems, which the target article characterized as having an outer loop that was executed once per task and an inner loop that was executed once per step of the task.
openaire   +1 more source

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano   +7 more
wiley   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Study of palmar dermatoglyphics in vitiligo and normal individuals [PDF]

open access: yesAl Ameen Journal of Medical Sciences, 2015
Background & Objective: Vitiligo is a common idiopathic & hereditary disease characterized by one or more patches of de-pigmented skin due to degeneration or disappearance of cutaneous melanocytes.
Azra Mubeen Karnul   +3 more
doaj  

Loops in dS/CFT

open access: yesJournal of High Energy Physics, 2021
We consider the semi-classical expansion of the Bunch-Davies wavefunction with future boundary condition in position space for a real scalar field, conformally coupled to a classical de Sitter background in the expanding Poincaré patch with quartic ...
Till Heckelbacher, Ivo Sachs
doaj   +1 more source

A study on loops and eddies identified from the trajectories of drifters in the North Indian Ocean

open access: yesOceanologia, 2021
We identify loops and eddies from the trajectories of the drifters in the North Indian Ocean (NIO) from October 1985 to March 2019. We use the geometric identification method to identify loops and eddies and compare them with the loops identified from ...
Shrikant Dora, S.G. Aparna
doaj   +1 more source

Loop-to-Loop Coupling [PDF]

open access: yes, 2012
This report estimates inductively-coupled energy to a low-impedance load in a loop-to-loop arrangement. Both analytical models and full-wave numerical simulations are used and the resulting fields, coupled powers and energies are compared. The energies are simply estimated from the coupled powers through approximations to the energy theorem.
Warne, Larry Kevin   +6 more
openaire   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

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