Results 51 to 60 of about 332,988 (266)
SCENARIO: Journal for Performative Teaching, Learning, Research, 2011 Our first Window of Practice contribution introduces a simple and effective language teaching technique called loops, which was developed as a part of the act and speak® method at Jeviste, a language school in Prague that specializes in using drama and ...
Dockalova, Bara
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Crumpled Polymer with Loops Recapitulates Key Features of Chromosome Organization
Physical Review X, 2023 Chromosomes are exceedingly long topologically constrained polymers compacted in a cell nucleus. We recently suggested that chromosomes are organized into loops by an active process of loop extrusion.
Kirill E. Polovnikov +5 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
DNA loops after cell lysis resemble chromatin loops in an intact nucleus
The Ukrainian Biochemical Journal, 2018 The comet assay has proved itself to be not only a method of detection of DNA damages at the level of individual cells but also an approach for investigation of spatial organization of DNA loop domains in nucleoids.
K. S. Afanasieva +2 more
doaj +1 more source
PLoS Biology, 2013 Most cells of a given species contain essentially the same complement of genes, yet individual genetically identical cells can assume dramatically different appearances and behaviours. This is achieved largely by the regulation of the transcription of individual genes, orchestrated by the specific binding of proteins to nearby sites in the genome—a ...
openaire +4 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Horizons of Observability in PT-symmetric Four-site Quantum Lattices
Acta Polytechnica, 2011 One of the key merits of PT-symmetric (i.e., parity times time reversal symmetric) quantum Hamiltonians H lies in the existence of a horizon of the stability of the system. Mathematically speaking, this horizon is formed by the boundary of the domain D(H)
M. Znojil
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source