A state-of-the-art machine learning pipeline for the analysis of spatial proteomics data
Organelle proteomics, or spatial proteomics, is the systematic study of protein sub-cellular localisation. Here, we focus on high-throughput quantitative mass spectrometry-based techniques such as LOPIT and PCP and demonstrate a robust and sound analysis
Laurent Gatto (637959)
core +1 more source
Supplemental Dataset 1: Resident organelle proteomes from LOPIT experiments (Fig. 2, S1) after SVM-based classification. Proteins are identified by their AGI accession code for the TAIR database.
Kathryn S. Lilley (73966) +25 more
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Principal components analysis plot (PCA) of the mouse stem cell dataset.
Proteins are clustered according to their density gradient distributions. Each point on the PCA plot represents one protein. Filled circles are the original protein markers used in classification, hollow circles show new locations as assigned by the SVM ...
Kathryn S. Lilley (73966) +9 more
core +1 more source
Analysis of the Interactome of the <i>Toxoplasma gondii</i> Tgj1 HSP40 Chaperone. [PDF]
Munera López J +9 more
europepmc +1 more source
The Second Asia-Oceania Human Proteome Organization (AOHUPO) Online Education Series on the Renaissance of Clinical Proteomics: Biomarkers, Imaging and Therapeutics. [PDF]
Low TY +6 more
europepmc +1 more source
Global Proteomics Indicates Subcellular-Specific Anti-Ferroptotic Responses to Ionizing Radiation. [PDF]
Christopher JA +5 more
europepmc +2 more sources
Semi-supervised Bayesian integration of multiple spatial proteomics datasets. [PDF]
Coleman S +6 more
europepmc +2 more sources
Proteomics Update and Perspectives from the Proteomics in Cell Biology and Disease Mechanisms Conference. [PDF]
Kotliar IB.
europepmc +1 more source
Operation of a TCA cycle subnetwork in the mammalian nucleus. [PDF]
Kafkia E +19 more
europepmc +1 more source
Dynamic subcellular proteomics identifies regulators of adipocyte insulin action. [PDF]
Conway OJ +14 more
europepmc +1 more source

