Results 131 to 140 of about 30,004 (213)

Hospital admissions and school absences of primary school children with and without neurodisability

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To inform integrated support by education and health services by comparing hospitalization and school absence rates during primary school in children with and without neurodisability. Method In this linked administrative data cohort study, we followed 2 351 589 children born in England between 2003 and 2008 from enrolment in Reception ...
Laura Gimeno   +23 more
wiley   +1 more source

Timing of insulin pump initiation among individuals with type 1 diabetes in Ontario, Canada

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims To assess characteristics associated with earlier (≤2 years since diagnosis) versus later (>2 years) insulin pump initiation among new type 1 diabetes applicants to the publicly funded insulin pump program in Ontario, and whether timing of pump initiation is associated with cumulative glycaemic exposure.
Xi Zhu   +5 more
wiley   +1 more source

Bexicaserin for the treatment of seizures in developmental and epileptic encephalopathies: A phase 1b/2a trial (PACIFIC)

open access: yesEpilepsia, EarlyView.
Abstract Objective This randomized, double‐blind, phase 1b/2a clinical trial was designed to evaluate the safety, tolerability, and efficacy of oral bexicaserin versus placebo for the treatment of seizures in adolescents and adults with developmental and epileptic encephalopathies (DEEs).
Dennis J. Dlugos   +74 more
wiley   +1 more source

What predicts improvements from home visits: Implementation fidelity or family enjoyment?

open access: yesFamily Relations, EarlyView.
Abstract Objective This study examined how implementation fidelity to Recipe 4 Success, a preventive intervention embedded within home visits, was related to family enjoyment of those home visits and how both implementation fidelity and enjoyment were related to improvements in parents' sensitive scaffolding and toddlers' self‐regulation.
Sarah M. Braaten   +6 more
wiley   +1 more source

17. Diabetes Advocacy: Standards of Care in Diabetes-2026. [PDF]

open access: yesDiabetes Care
American Diabetes Association Professional Practice Committee for Diabetes* .
europepmc   +1 more source

The structural, functional, and therapeutic potential of metacaspases in fungi and protozoa

open access: yesThe FEBS Journal, EarlyView.
Metacaspases are Ca2+‐dependent cysteine proteases whose structural characteristics, particularly calcium binding and autocatalytic processing, govern their activation and biological functions. These enzymes differ among microorganisms and regulate their cell cycles, making them excellent targets for drug development.
Ane C. M. Duarte   +9 more
wiley   +1 more source

Engineering Chimeric Hypoallergens for Safer and More Effective House Dust Mite Allergy Vaccines

open access: yes
Clinical &Experimental Allergy, EarlyView.
Eduardo S. da Silva   +17 more
wiley   +1 more source

Elucidating the Molecular Basis in a Cohort of Patients With Combined Bleeding Tendencies and Joint Hypermobility Manifestations

open access: yesHaemophilia, EarlyView.
ABSTRACT Background In patients with unexplained bleeding and normal haemostatic parameters, heritable disorders of connective tissue (HDCT) may be an underlying cause due to vascular fragility, as observed in Ehlers–Danlos syndrome (EDS) or Marfan syndrome (MS). This study aims to investigate the molecular profile of patients with joint hypermobility (
Perla Bandini   +11 more
wiley   +1 more source

Interobserver variability of histopathological assessment in pT1 colorectal carcinoma

open access: yesHistopathology, EarlyView.
Interobserver variability among 20 gastrointestinal pathologists was evaluated on 80 pT1 colorectal carcinoma cases. A pilot phase was followed by a consensus meeting, then a larger concordance study was performed. High interobserver agreement was achieved after consensus for histological grade, lymphovascular invasion, tumour budding, poorly ...
Karmele Saez de Gordoa   +24 more
wiley   +1 more source

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