Results 171 to 180 of about 10,097 (263)

Amyloid‐Forming Amylin Secreted by the Pancreas Promotes Hypoxia‐Inducible Factor Activation and Mitochondrial Alterations in Liver and Heart During Type 2 Diabetes Pathogenesis

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
Human amylin is secreted from the pancreas of HIP rats and is amyloidogenic, forming aggregates systemically. In comparison with age‐matched control (WT), hyperglycemic (UCD) and amylin knockout rats (AKO), HIP rats showed increased hypoxia‐inducible factors (HIF‐1/2) in heart and liver, alongside alterations in mitochondrial electron transfer system ...
Alice E. Knapton, Nirmal Verma, Deepak Kotiya, Alice P. Sowton, Benjamin D. Thackray, Lorenz M. W. Holzner, Paula M. Darwin, Sanda Despa, Florin Despa, Andrew J. Murray   +9 more
wiley   +1 more source

Mutual information minimization enhances noise robustness and induces fault containment in functionally differentiated recurrent neural networks. [PDF]

Front Neurosci
Tomoda Y, Yamaguti Y.
europepmc   +1 more source

Hepatic HIF2α Modulates Extra‐Hepatic Disease‐Associated Phenotypes During Metabolic Dysfunction‐Associated Steatotic Liver Disease

Comprehensive Physiology, Volume 16, Issue 5, October 2026.
High fat, high fructose, high cholesterol “GAN” diet feeding in mice induces MASLD, cardiac dysfunction, loss of lean mass, and hyperinsulinaemia. Hepatocyte‐specific deletion of HIF2α also causes cardiac dysfunction and loss of lean mass but prevents GAN induced hyperinsulinaemia and cardiac sympathetic dominance without preventing MASLD.
Lorenz M. W. Holzner, Rosa M. Korpershoek, Youguo Niu, Anna Cochrane, Paula M. Darwin, Julia Babuta, Areesha Nazeer, Cecilia Castro, Alice P. Sowton, Alice E. Knapton, Benjamin D. Thackray, Julian L. Griffin, Zoe Hall, Dino A. Giussani, Rob C. I. Wüst, Andrew J. Murray   +15 more
wiley   +1 more source

Beyond the Hospital: Spatial Inequality and Structural Divergence in Stroke Mortality Across the United States (2020-2024). [PDF]

Cureus
Acosta-Batista C, Sibello Deustua S, Perez Santiago M, Bryan J, López Sánchez A, Gonzalez Reyes N, Brana Miranda RC, Contino Rivero A, Santana Mercedes FJ, Diaz Perez L, Blanco Espinosa E.   +10 more
europepmc   +1 more source

Does Mother Provide? Re‐Examination of Maternal and Embryonic Microbiomes of Diploptera punctata

Ecology and Evolution, Volume 16, Issue 10, October 2026.
This figure summarizes the compositional differences in the non‐blattabacterial microbiomes of embryonic and adult females of the viviparous, Diploptera punctata. This shows the non‐negligible presence and possibly maternal sources of these bacterial taxa in developing embryos.
Brennan Jonas, Victoria Arrowsmith, Paul Ayayee   +2 more
wiley   +1 more source

Extreme vulnerability to intruder attacks destabilizes network dynamics. [PDF]

Nat Commun
Nazerian A, Tangerami S, Asllani M, Phillips D, Makse H, Sorrentino F.   +5 more
europepmc   +1 more source

PGE2 Enhances Human ILC3 Function but Constrains ILC2‐to‐ILC3 Plasticity

European Journal of Immunology, Volume 56, Issue 10, October 2026.
Distinct prostaglandin circuits regulate human ILC2 and ILC3 function. ILC3‐derived PGE2 promotes type 3 cytokine production, whereas hybrid ILC2/3 generated during plasticity retain an inhibitory response to PGE2 despite acquiring ILC3‐like features. ABSTRACT Type 2 innate lymphoid cells (ILC2) drive eosinophilic asthma, whereas ILC3 and plastic ILC2 ...
Lorenz Wirth, Whitney Weigel, Efthymia Kokkinou, Johan Kolmert, Anna‐Karin Johnsson, Alessandro Quaranta, Craig Wheelock, Mattias Jangard, Ram V. Pandey, Sven‐Erik Dahlén, Christopher Andrew Tibbitt, Thomas Hochdörfer, Jenny Mjösberg   +12 more
wiley   +1 more source

Modeling and optimizing mileage homogeneity in public transportation using Gini index. [PDF]

Sci Rep
Sevim B, Ayvaz B, Eldemir F.
europepmc   +1 more source

QG‐Python: A Reproducible 1.5‐Layer Quasi‐Geostrophic Modelling Service With Direct Sparse Solvers, Spectral Stability Diagnostics and Filter Sensitivity Data

Geoscience Data Journal, Volume 13, Issue 4, October 2026.
QG‐Python is an open, reproducible 1.5‐layer quasi‐geostrophic modelling service whose published diagnostics show that the classical von Neumann bound underestimates the true Leapfrog stability limit by a factor of 13.7, and that the Robert–Asselin–Williams filter reduces kinetic energy and enstrophy biases from ~21% and ~45% to under 4%.
Elias D. Nino‐Ruiz
wiley   +1 more source

Better road conditions for everyone can be a co-benefit of road maintenance. [PDF]

Sci Rep
Dadzoe F, Boakye J, Okte E.
europepmc   +1 more source