Results 81 to 90 of about 6,352,796 (319)

AMPDECIDE amputation level patient decision aids: a feasibility study

BMC Medical Informatics and Decision Making
Objective This was a feasibility study of the AMPDECIDE amputation level selection patient decision aids (one transmetatarsal vs. transtibial, the other transtibial vs. transfemoral) designed to inform a larger efficacy trial.
Alison W. Henderson, Maryam Soltani, Bjoern D. Suckow, Alison R. Kern, Daniel D. Matlock, Joseph M. Czerniecki, Daniel C. Norvell   +6 more
doaj   +1 more source

Views of knowledge users on recurrent miscarriage services and supports in the Republic of Ireland: a qualitative interview study

BMJ Open
Objectives Women and men/partners who experience miscarriage often report poor care experiences within health services around the time of miscarriage and beyond; less is known about recurrent miscarriage (RM) care.
Karen Matvienko-Sikar, Marita Hennessy, Keelin O’Donoghue, Rebecca Dennehy, Con Lucey, Ria O’Sullivan-Lago, Jennifer Uí Dhúbhgáin   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Intrapartum fetal deaths and unexpected neonatal deaths in the Republic of Ireland: 2011 – 2014; a descriptive study

BMC Pregnancy and Childbirth, 2018
Background Intrapartum fetal death, the death of a fetus during labour, is a tragic outcome of pregnancy. The intrapartum death rate of a country is reflective of the care received by mothers and babies in labour and it is through analysing these cases ...
K. McNamara, K. O’Donoghue, R. A. Greene   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Reati denunciati: statuto e carte giudiziarie bolognesi della fine del Tredicesimo secolo a confronto

, 2020
Il saggio si occupa della denuncia come strumento di governo e cerca di ricostruire le disposizioni statutarie in materia a partire dal caso bolognese, concentrandosi soprattutto sugli statuti del 1288.
Edward Loss
core  

Loss of vision

Practical Neurology, 2010
Visual loss is not uncommon and many patients end up seeing neurologists because of it. There is a long list of possible causes but in most patients visual loss is associated with visual field loss. This means that for practical purposes the differential diagnosis can usually be narrowed down to a manageable shortlist by consideration of where in the ...
openaire   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

My loss is my loss

, 2014
UK touring exhibition developed by University of Manchester with AHRC funding. My Loss is My Loss (patchwork of used lottery tickets) was selected for exhibition.
Williams, Rhiannon
core  

Development and testing of a new method to combine environmental management tools to improve life cycle management performance at industrial level [PDF]

, 2017
Environmental sustainable development topic is increasingly at the centre of international interest. During the last decades, environmental issues have evolved from pollution and depletion of natural resources towards global issues such as climate ...
Loss, Andrea
core