Results 151 to 160 of about 7,181,199 (327)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Protein quality assessment with a loss function designed for high-quality decoys. [PDF]

Front Bioinform, 2023
Roy S, Ben-Hur A.
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Laboratory markers predict bone loss in Crohn's disease: relationship to blood mononuclear cell function and nutritional status [PDF]

, 2004
T. M. Trebble, Stephen A. Wootton, Mike Stroud, Mark Mullee, Philip C. Calder, David Fine, Caje Moniz, Nigel K. Arden   +7 more
openalex   +1 more source

The Implementation of the K-Medoid Clustering for Grouping Hearing Loss Function on Excessive Smartphone Use

, 2023
Eri Wahyudi, Dwiny Meidelfi, Nofrizal Nofrizal, Zulfan Saam, M Juandi   +4 more
openalex   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Ordinal Regression Research Based on Dual Loss Function-An Example on Lumbar Vertebra Classification in CT Images. [PDF]

Diagnostics (Basel)
Tang CP, Chang HY, Hsu YM, Lin TL.
europepmc   +1 more source

Self-adaption and texture generation: A hybrid loss function for low-dose CT denoising. [PDF]

J Appl Clin Med Phys, 2023
Wang Z, Liu M, Cheng X, Zhu J, Wang X, Gong H, Liu M, Xu L.   +7 more
europepmc   +1 more source

Additional file 1: of A loss-of-function genetic screening reveals synergistic targeting of AKT/mTOR and WTN/β-catenin pathways for treatment of AML with high PRL-3 phosphatase

, 2018
Jianbiao Zhou, Sabrina Hui Min Toh, Zit-Liang Chan, Jessie Yiying Quah, Jing-Yuan Chooi, Tuan Zea Tan, Phyllis S.Y. Chong, Qi Zeng, Wee Joo Chng   +8 more
openalex   +1 more source

Dust driven mass loss from carbon stars as function of stellar parameters - II. Effects of grain size on wind properties [PDF]

, 2011
Lars Mattsson, S. Höfner
openalex   +1 more source