The establishment and application of quality gain-loss function when the loss of primary and cubic term is not ignored and the compensation quantity is constant. [PDF]
PLoS One, 2023 Wang B, Li X, Shi J, Li Q, Nie X.
europepmc +1 more source
Reduced platelet count, but no major platelet function abnormalities, are associated with loss-of-function ATP-binding cassette-1 gene mutations [PDF]
, 2017 Pietro Minuz +11 more
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Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A Method for Constructing a Loss Function for Multi-Scale Object Detection Networks. [PDF]
Sensors (Basel)Wang D, Zhu H, Zhao Y, Shi J.
europepmc +1 more source
U-Net Architecture for Prostate Segmentation: The Impact of Loss Function on System Performance. [PDF]
Bioengineering (Basel), 2023 Montazerolghaem M +3 more
europepmc +1 more source
On Loss Functions for Deep Neural Networks in Classification
, 2017 Katarzyna Janocha +1 more
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From Next Generation Sequence to the Phenotype: Exploring the Bainbridge-Ropers Syndrome with Loss of Function Variants in ASXL3 [PDF]
, 2019 Silvina Contreras‐Capetillo +1 more
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E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Robust propensity score estimation via loss function calibration. [PDF]
Stat Methods Med ResShang Y, Chiu YH, Kong L.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source