Results 191 to 200 of about 7,181,199 (327)

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders [PDF]

open access: green, 2016
Tarjinder Singh   +61 more
openalex   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

open access: yesFEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas   +6 more
wiley   +1 more source

A Topological Loss Function for Deep-Learning Based Image Segmentation Using Persistent Homology. [PDF]

open access: yesIEEE Trans Pattern Anal Mach Intell, 2022
Clough JR   +5 more
europepmc   +1 more source

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