Results 81 to 90 of about 389,923 (287)

Load Concentration Factor Based Analytical Method for Optimal Placement of Multiple Distribution Generators for Loss Minimization and Voltage Profile Improvement

Energies, 2016
This paper presents novel separate methods for finding optimal locations, sizes of multiple distributed generators (DGs) simultaneously and operational power factor in order to minimize power loss and improve the voltage profile in the distribution ...
Mohsin Shahzad, Ishtiaq Ahmad, Wolfgang Gawlik, Peter Palensky   +3 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Minimization of Transmission Line Losses Through System Topology Reconfiguration

Energies
This research proposes a methodology for minimizing losses in transmission lines (TLs), considering the reconfiguration of the architecture of the electrical power system (EPS). The implementation of this methodology redirects the power flow with optimal
David Orbea, Diego Carrión, Manuel Jaramillo   +2 more
doaj   +1 more source

Minimize Boiler Short Cycling Losses [PDF]

, 2006
This revised ITP tip sheet on minimizing boiler short cycling losses provides how-to advice for improving industrial steam systems using low-cost, proven practices and technologies.
openaire   +2 more sources

Conditional Density Estimation with Dimensionality Reduction via Squared-Loss Conditional Entropy Minimization [PDF]

, 2014
Regression aims at estimating the conditional mean of output given input. However, regression is not informative enough if the conditional density is multimodal, heteroscedastic, and asymmetric.
Sugiyama, Masashi, Tangkaratt, Voot, Xie, Ning   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Loss Minimization-Based Sensorless Control of High-Speed Induction Motor Considering Core Loss

IEEE Access
This paper presents loss-minimizing sensorless control (LMC) strategies utilized to optimize the energy of high-speed induction motor (HSIM) drives. A machine’s ability to operate effectively depends on the estimation of its electrical losses ...
Tadele Ayana, Piotr Kolodziejek, Marcin Morawiec, Lelisa Wogi   +3 more
doaj   +1 more source

Robust Kernel Principal Component Analysis With ℓ_2,1-Regularized Loss Minimization

IEEE Access, 2020
Principal component analysis (PCA) is a widely used unsupervised method for dimensionality reduction. The kernelized version is called kernel principal component analysis (KPCA), which can capture the nonlinear data structure.
Duo Wang, Toshihisa Tanaka
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source