Results 71 to 80 of about 2,425,724 (292)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Minimizing transmission loss using inspired ant colony optimization and Markov Chain Monte Carlo in underwater WSN environment

Journal of Ocean Engineering and Science, 2019
In Underwater Wireless Sensor Networks (UWSNs), the most important challenging issues are propagation delay, high error probability, high latency, high communication cost, limited bandwidth, limited memory, low packet delivery ratio, and transmission ...
Raj Priyadarshini R, Sivakumar N
doaj   +1 more source

Probability of loss reversal in Australia

Australian Journal of Management, 2016
Investors in loss firms assess the likelihood of these firms reverting to profit (i.e. loss reversal). This research examines the factors useful for predicting future loss reversal in the Australian market. Specifically, it focuses on loss firms’ investment activities, in addition to factors examined in previous US literature.
openaire   +2 more sources

Hospital Readmission After Traumatic Brain Injury Hospitalization in Community‐Dwelling Older Adults

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the risk of hospital readmission after an index hospitalization for TBI in older adults. Methods Using data from the Atherosclerosis Risk in Communities (ARIC) study, we used propensity score matching of individuals with an index TBI‐related hospitalization to individuals with (1) non‐TBI hospitalizations (primary analysis)
Rachel Thomas, Connor A. Law, Joan A. Casey, Thomas Mosley, Rebecca F. Gottesman, Ramon Diaz‐Arrastia, Holly Elser, Andrea L. C. Schneider   +7 more
wiley   +1 more source

Reliability-based evaluation of scour around dual bridge piers

Građevinar, 2019
The causes of uncertainty involved in temporal variation of the depth of cavern formation due to clear water scouring at dual piers with tandem arrangement are identified in this study. In an example, the probability of failure induced by scouring around
Meric Yilmaz, Melih Calamak, A. Melih Yanmaz   +2 more
doaj   +1 more source

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Probability Distortion and Loss Aversion in Futures Hedging [PDF]

We analyze how the introduction of probability distortion and loss aversion in the standard hedging problem changes the optimal hedge ratio. Based on simulated cash and futures prices for soybeans, our results indicate that the optimal hedge changes ...
Garcia, Philip, Mattos, Fabio, Pennings, Joost M.E.   +2 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source

Analysis of loss probabilities on the call level and packet level in a multi-rate system

Tongxin xuebao, 2007
A systematic research on the performance analysis on the call level and the packet level in a system with multi-rate VBR services was made.According to the global balance condition of a multi-dimensional Markov chain,an algorithm of accurately evaluating
JIANG Hong-yan, LIN Ya-ping, HUANG Sheng-ye   +2 more
doaj   +2 more sources