By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source
Rehabilitation and Techno design of Distribution transformer and 11kV feeder of a radial distribution system [PDF]
In any transmission and distribution system- the performance of that system mainly depends on voltage regulation and efficiency. Hence for the better operation of the system, it is required to maintain constant voltage regulation with good power factor ...
Abdul Saleem Shaik +2 more
doaj +1 more source
Pressure dependence of the dielectric loss in semi-conducting polypyrrole aged at room temperature
The effect of physical aging of semi-conducting polypyrrole at ambient temperature for two years duration on the dielectric loss at various pressures is investigated.
A.N. Papathanassiou +29 more
core +1 more source
Loss reduction in electromechanically tunable microring cavities
Nanophotonic structures coupled with mechanics enable large effective index perturbation. To date, however, the relation between index tuning and induced optical loss has not been considered in detail. In this work we present an in-depth study of optical loss mechanisms in an electromechanically-tunable waveguide filter. Gradient electric forces modify
Marcel W. Pruessner +6 more
openaire +2 more sources
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
The role and implications of mammalian cellular circadian entrainment
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
LEAN-TECHNOLOGIES AS A RESOURCE OF EDUCATION MODERNIZATION
The article examines domestic practices of reducing losses in educational organizations. Attention has been paid to the activities of educational organizations aimed at reducing losses, both in the main production processes, and in the auxiliary ...
A. R. Groshev, G. E. Karataeva
doaj
Development of the system of management accounting of costs of the railway transport complex
In order to improve the efficiency of long distance transport, it is necessary for all participants in the process to optimize the costs of infrastructure services by introducing advanced technologies for the organization of the transportation process ...
O. F. Miroshnichenko, A. E. Oginskaya
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source

