Results 121 to 130 of about 4,990,585 (300)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
ACTIVE POWER LOSS REDUCTION BY ASSORTED ALGORITHMS
International Journal of Research -GRANTHAALAYAH, 2018 This paper presents assorted algorithms for solving optimal reactive power problem. Symbiosis modeling (SM), which extends the dynamics of the canonical PSO algorithm by adding a significant ingredient that takes into account the symbiotic co evolution between species, Hybridization of Evolutionary algorithm with Conventional Algorithm (HCA) that ...
openaire +2 more sources
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Advanced operation of heated fluidic resonators via mechanical and thermal loss reduction in vacuum. [PDF]
Microsyst Nanoeng, 2023 Ko J, Lee BJ, Lee J.
europepmc +1 more source
An assessment of secondary loss reduction techniques for STME LOX turbine [PDF]
One of the primary objectives of the National Launch System (NLS) program, explored jointly by NASA and several other government agencies, is to develop a new Space Transportation Main Engine (STME) which will perform better and is more reliable than the
Chyu, Mingking K.
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Zhongguo dianliUnder the background of high proportion distributed resource access, in order to fully explore the loss reduction potential of reactive power regulation of the distribution network and reach the target of loss reduction through reactive power ...
Xiping MA +4 more
doaj +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source