Results 111 to 120 of about 5,808,650 (308)
ESTUDO DE VAZÕES MÍNIMAS Q1,10 e Q7,10 DE RIOS DO PARANÁ SEGUNDO DISTRIBUIÇÃO GENERALIZADA
Uma das funções oferecidas pela água é a manutenção de vazões mínimas que suportem o ecossistema aquático. Os cursos d’água desde muito tempo têm sido utilizados como receptores de efluentes domésticos, industriais e agro-industriais. A carga de efluente
Manoel Moisés Ferreira de Queiroz +3 more
doaj
Long Lost Freshmen Traditions: The Infamous Dink [PDF]
Hello and happy Wednesday everyone! This week I have been submerged in a past world in which harassing freshmen was a college sanctioned activity. This chapter in Gettysburg College history finds a voice within my unprocessed collection thanks to the ...
Green, Sierra R.
core +1 more source
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Every town hss its own architectural performance. And architecture is not merely a physical landscape of buildings in a town,, as seen by the observer, but it has a deeper mening, which displays the art of structures and constructions.
Benny Poerbantanoe
doaj
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Catches in ghost-fishing octopus and fish traps in the northeastern Atlantic Ocean (Algarve, Portugal) [PDF]
Ghost fishing is the term used to describe the continued capture of fish and other living organisms after a fisherman has lost all control over the gear.
Bentes, Luís +6 more
core +1 more source
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source

