Results 41 to 50 of about 8,360 (304)

Unitary Owen Points in Cooperative Lot-Sizing Models with Backlogging

open access: yesMathematics, 2021
This paper analyzes cost sharing in uncapacitated lot-sizing models with backlogging and heterogeneous costs. It is assumed that several firms participate in a consortium aiming at satisfying their demand over the planning horizon with minimal operating ...
Luis A. Guardiola   +2 more
doaj   +1 more source

Optimal selling price, replenishment lot size and number of shipments for two-echelon supply chain model with deteriorating items [PDF]

open access: yesDecision Science Letters, 2018
This paper deals with a pricing and production-distribution model for a deteriorating item in a two-echelon supply chain. The profit function for the manufacturer and retailer in the integrated supply chain is derived. The manufacturer's production batch
Amir Nasiri pour   +1 more
doaj   +1 more source

Health‐Related Quality of Life and Symptom Severity Among Patients With PIK3CA‐Related Overgrowth Spectrum: A Mixed‐Methods Study to Understand Real‐World Experience With Alpelisib Treatment

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu   +8 more
wiley   +1 more source

Serological Benefit of SARS‐CoV‐2 Vaccination Relative to Infection in Children With Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro   +11 more
wiley   +1 more source

Competition under Capacitated Dynamic Lot Sizing with Capacity Acquisition [PDF]

open access: yes, 2010
Lot-sizing and capacity planning are important supply chain decisions, and competition and cooperation affect the performance of these decisions.
Li, H, Meissner, J
core  

An optimization framework for solving capacitated multi-level lot-sizing problems with backlogging

open access: yes, 2011
This paper proposes two new mixed integer programming models for capacitated multi-level lot-sizing problems with backlogging, whose linear programming relaxations provide good lower bounds on the optimal solution value. We show that both of these strong
Akartunali, Kerem   +7 more
core   +1 more source

Note—Learning Effects in Economic Lot Sizing [PDF]

open access: yesManagement Science, 1983
The classical square-root formula for optimal lot size is a useful tool especially for those manufacturing processes in which labor intensive items are produced in small quantities. There is a class of stationary lot sizing problems to which this formula applies.
Muth, Eginhard J., Spremann, Klaus
openaire   +4 more sources

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Economic Lot Sizing and Scheduling in Distributed Permutation Flow Shops [PDF]

open access: yesJournal of Optimization in Industrial Engineering, 2019
This paper addresses a new mixed integer nonlinear and linear mathematical programming economic lot sizing and scheduling problem in distributed permutation flow shop problem with number of identical factories and machines.
Mohammad Alaghebandha   +2 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

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