Results 71 to 80 of about 86,998 (307)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Firefly Algorithm: Minimizing Cost on Single-Level Lot-Sizing Problem

open access: yesJournal of Computing Research and Innovation, 2018
Nowadays, the industrial company plays a very important role to our country. However, the manufacturer industry has big issues in the production planning which called planning horizon where, the lot-sizing problem is one of the most important issues in ...
Siti Hafawati Jamaluddin   +3 more
doaj  

Implementasi Algoritma Wagner-Within pada Manajemen Inventori di PT X

open access: yesBusiness and Finance Journal, 2018
The increasing competition in the manufacturing industry caused increasing inconsumer demand of the quality and quantity of a good product. Therefore, manufacturing companies must have reliable services, policies and product qualities to satisfy its ...
Puspandam Katias, Achmad Affandi
doaj   +1 more source

Four equivalent lot-sizing models [PDF]

open access: yes
We study the following lot-sizing models that recently appeared in the literature: a lot-sizing model with aremanufacturing option, a lot-sizing model with production time windows, and a lot-sizing model with cumulativecapacities. We show the equivalence
Heuvel, W. van den, Wagelmans, A.P.M.
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Analisa Persediaan Material Pada Proyek Pembangunan Jembatan Sungai Brantas Di Ruas Tol Kertosono-Mojokerto

open access: yesJurnal Teknik ITS, 2014
Proyek Pembangunan Jembatan Sungai Brantas merupakan tahap dari pelaksanaan proyek Jalan Tol Kertosono-Mojokerto dimana jalan tol ini akan terhubung dengan Jalan Tol Surabaya-Mojokerto.
Titis Wahyu Pratiwi   +2 more
doaj  

Developing and Solving a Two Level Lot Sizing Problem [PDF]

open access: yesچشم‌انداز مدیریت صنعتی, 2017
In This Article, a two level lot sizing problem with multi production methods and fuzzy demand is presented.The objective of the model is to minimize the costs.Various approaches like Genetic Algorithm (GA), Simulated Annealing (SA) and Vibration Damping
Mohammad Ebrahimi, Maghsoud Amiri
doaj  

Lot-sizing with stock upper bounds and fixed charges [PDF]

open access: yes
Here we study the discrete lot-sizing problem with an initial stock variable and an associated variable upper bound constraint. This problem is of interest in its own right, and is also a natural relaxation of the constant capacity lot-sizing problem ...
DI SUMMA, Marco, WOLSEY, Laurence A.
core  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Note—Lot-Sizing and Sequencing Delays [PDF]

open access: yesManagement Science, 1987
In production scheduling, time performance is usually taken to be the province of sequencing models which take task processing times to be given. However, in practice, processing times can often be controlled by the choice of lot sizes which thus have a major impact on makespan, waiting times, flow times and other measures.
openaire   +1 more source

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