Results 71 to 80 of about 8,360 (304)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Incorporating demand uncertainty and forecasting in supply chain planning models [PDF]

open access: yes, 2011
This paper develops a framework for examining the effect of demand uncertainty and forecast error on unit costs and customer service levels in the supply chain, including Material Requirements Planning (MRP) type manufacturing systems.
R Fildes   +3 more
core   +1 more source

Analisa Persediaan Material Pada Proyek Pembangunan Jembatan Sungai Brantas Di Ruas Tol Kertosono-Mojokerto

open access: yesJurnal Teknik ITS, 2014
Proyek Pembangunan Jembatan Sungai Brantas merupakan tahap dari pelaksanaan proyek Jalan Tol Kertosono-Mojokerto dimana jalan tol ini akan terhubung dengan Jalan Tol Surabaya-Mojokerto.
Titis Wahyu Pratiwi   +2 more
doaj  

Developing and Solving a Two Level Lot Sizing Problem [PDF]

open access: yesچشم‌انداز مدیریت صنعتی, 2017
In This Article, a two level lot sizing problem with multi production methods and fuzzy demand is presented.The objective of the model is to minimize the costs.Various approaches like Genetic Algorithm (GA), Simulated Annealing (SA) and Vibration Damping
Mohammad Ebrahimi, Maghsoud Amiri
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

A heuristic approach for big bucket multi-level production planning problems

open access: yes, 2009
Multi-level production planning problems in which multiple items compete for the same resources frequently occur in practice, yet remain daunting in their difficulty to solve. In this paper, we propose a heuristic framework that can generate high quality
Akartunali, Kerem, Miller, Andrew
core   +1 more source

PENGARUH PENENTUAN JUMLAH PEMESANAN PADA BULLWHIP EFFECT

open access: yesJ@ti Undip: Jurnal Teknik Industri, 2017
Bullwhip effect adalah suatu kondisi dimana terjadi peningkatan variasi permintaan dalam suatu rantai pasok. Bullwhip effect ini dapat diakibatkan oleh beberapa faktor salah satunya yaitu jumlah pemesanan.
Puji Lestari   +2 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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