Results 21 to 30 of about 274,480 (202)

Un observatoire parmi les lieux d’observation du ciel : le projet de l’Observatoire royal de Louis XIV au prisme de son nom

open access: yesCahiers d’histoire, 2017
Qu’est-ce qu’un observatoire ? Quels furent les premiers observatoires de l’histoire ? Dans cette étude, nous montrerons que le choix du nom « observatoire » pour l’Observatoire royal de Paris, fondé pour Louis XIV et pour l’Académie royale des sciences,
Dalia Deias
doaj   +1 more source

Les regalia au crible de la caricature du xvie au xviiie siècle

open access: yesBulletin du Centre de Recherche du Château de Versailles, 2006
The purpose of this article is to show how the attributes of the monarchy, also named regalia, are used in a negative way in polemical images and caricatures since the sixteenth century.
Annie Duprat
doaj   +1 more source

Farnesyltransferase Deficiency in Cardiomyocytes Initiates Senescence and Contributes to Cardiac Fibrosis

open access: yesAdvanced Science, EarlyView.
Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen   +16 more
wiley   +1 more source

Gut Mycobiota‐Associated Tryptophan Catabolites Protect Against Metabolic Dysfunction‐Associated Steatotic Liver Disease

open access: yesAdvanced Science, EarlyView.
ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao   +11 more
wiley   +1 more source

La fin d’une longue attente. Le 16 Novembre 1700 dans les Mémoires du duc de Saint-Simon

open access: yesLes Dossiers du GRIHL, 2017
Charles II of Spain died on November 1, in Madrid. Once this information is known in Versailles, Louis XIV must surely take the most important decision of his reign: Should he accept the will of Charles II and proclaim his grandson Philip of Anjou King ...
Sven Externbrink
doaj   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu   +4 more
wiley   +1 more source

Marion Brétéché, Les Compagnons de Mercure: Journalisme et politique dans l’Europe de Louis XIV

open access: yesBMGN: Low Countries Historical Review, 2016
Marion Brétéché, Les Compagnons de Mercure: Journalisme et politique dans l’Europe de Louis XIV (Dissertatie Université Paris-Sorbonne; Ceyzérieu: Champ Vallon, 2015, 356 pp., isbn 979 1 02670 022 7).
Margaret C. Jacob
doaj   +1 more source

« Ah ! Mignard que vous louez bien ! » : Le secret et le sacré dans le portrait de Madame de Maintenon

open access: yesBulletin du Centre de Recherche du Château de Versailles, 2021
This article offers a new interpretation of the portrait of Madame de Maintenon, in which Pierre Mignard depicted the secret wife of Louis XIV as Saint Frances of Rome. Celebrated in its time as a witty conceit, the portrait has been taken at face value,
Lars Cyril Nørgaard, Eelco Nagelsmit
doaj   +1 more source

Louvre Museum - Paintings [PDF]

open access: yes, 2018
The Louvre Museum is the largest of the world's art museums by its exhibition surface. These represent the Western art of the Middle Ages in 1848, those of the ancient civilizations that preceded and influenced it (Oriental, Egyptian, Greek, Etruscan and
Sfetcu, Nicolae
core  

A microdialysis technique for continuous subcutaneous glucose monitoring in diabetic patients (part 1) [PDF]

open access: yes
Lettre de Louis Phélypeaux de Pontchartrain (secrétaire d'Etat de la Marine et de la Maison du roi) à Gabriel Nicolas de La Reynie (lieutenant général de police de Paris) datée du 27 mars 1693. In: Correspondance administrative sous le règne de Louis XIV,
Poscia, A   +8 more
core   +1 more source

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