A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim +9 more
wiley +1 more source
On the Recycling of Water Atomized Powder and the Effects on Properties of L-PBF Processed 4130 Low-Alloy Steel. [PDF]
Abdelwahed M +5 more
europepmc +1 more source
Water‐Soluble, Enzyme‐Degradable, and Hydrolyzable STAR Particles for Enhanced Drug Delivery to Skin
Biodegradable polymer STAR particles fabricated from water‐soluble, enzyme‐degradable, and hydrolyzable materials significantly enhance intradermal drug delivery. By replacing conventional non‐biodegradable materials, these STAR particles address environmental and safety concerns while expanding the potential of skin‐based drug delivery technologies ...
Aydin Sadeqi +2 more
wiley +1 more source
Wear-Resistance Improvement of 65Mn Low-Alloy Steel through Adjusting Grain Refinement by Cyclic Heat Treatment. [PDF]
Tong Y +4 more
europepmc +1 more source
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave +8 more
wiley +1 more source
Effect of Molybdenum on the Impact Toughness of Heat-Affected Zone in High-Strength Low-Alloy Steel. [PDF]
Wu X +8 more
europepmc +1 more source
How is Nanoarchitectonics Shaping Extracellular Vesicle Research?
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake +5 more
wiley +1 more source
Automatic Segmentation and Recognition of the Microstructure of High-Strength Low-Alloy Steel. [PDF]
Wang L +7 more
europepmc +1 more source
Experimental and Numerical Study of Combined High and Low Cycle Fatigue Performance of Low Alloy Steel and Engineering Application. [PDF]
Tang Z +5 more
europepmc +1 more source
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto +10 more
wiley +1 more source

