Results 71 to 80 of about 3,149,253 (308)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Low cost submarine robot [PDF]

open access: yesSongklanakarin Journal of Science and Technology (SJST), 2010
A submarine robot is a semi-autonomous submarine robot used mainly for marine environmental research. We aim todevelop a low cost, semi-autonomous submarine robot which is able to travel underwater.
Ponlachart Chotikarn   +3 more
doaj  

Low cost solar energy collection system [PDF]

open access: yes, 1977
A fixed, linear, ground-based primary reflector having an extended, curved sawtooth contoured surface covered with a metallized polymeric reflecting material, reflected solar energy to a movably supported collector that was kept at the concentrated line ...
Miller, C. G., Stephans, J. B.
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Structured early childhood education exposure and childhood cognition – Evidence from an Indian birth cohort

open access: yesScientific Reports
Experiences in early childhood form the bedrock of future human potential. In impoverished settings, structured early childhood education (ECE) in preschool years can augment overall childhood and later human abilities.
Beena Koshy   +7 more
doaj   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Large benefits, low cost. [PDF]

open access: yes
Is the government's National Literacy Strategy effective? Stephen Machin and Sandra McNally look at the evidence from the pilot project.
Machin, Stephen, McNally, Sandra
core   +1 more source

Flexible, low-cost silicon solar cell arrays [PDF]

open access: yes, 1972
Silicon solar cell arrays are pressure-bonded to flexible backing and protected by fluorinated ethylene propylene cover in one mechanized operation.
Bernatowicz, D. T.   +2 more
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Low Cost, Adhesion Strength Based Cell Sorter [PDF]

open access: yes, 2017
In many in vitro experiments, primary cells are harvested from an animal species to undergo experimental manipulation and subsequent analysis. Cell sorters are a luxury to have after cell harvesting to ensure pure populations of cells.
Burtch, Emily   +3 more
core   +2 more sources

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