Results 181 to 190 of about 585,431 (288)

Establishment of a mouse model of TMAO‐induced cardiac injury and application of MICT intervention

Animal Models and Experimental Medicine, EarlyView.
This study aims to explore the establishment of an animal model of cardiac injury induced by trimethylamine‐N‐oxide (TMAO), a metabolite secreted by gut microorganisms, and to investigate its application in moderate‐intensity continuous training (MICT) intervention.
Zhongping Xie, Hong Zou, Lijing Gong, Minghui Lin, Caihua Huang   +4 more
wiley   +1 more source

Characterization of the low-density lipoprotein receptors family and identification of vitellogenin receptors in Mugil cephalus. [PDF]

Sci Rep
Miccoli A, Randazzo B.
europepmc   +1 more source

Quantitative proteomics identifies clusterin as a novel biomarker for atherosclerosis

Animal Models and Experimental Medicine, EarlyView.
This schematic illustrates the proposed mechanism. In advanced atherosclerotic lesions, upregulated CLU on the cell surface activates low‐density lipoprotein (LDL) receptor‐related protein 1 (LRP1). This interaction triggers the phosphorylation and activation of AKT.
Dengfeng Ding, Yingjie Zhang, Li Zhang, Xinou Zheng, Miaomiao Niu, Yunxiao Jia, Xuezhuang Li, Hua Chen, Chao Guo, Tao Jiang, Yuqiong Zhao   +10 more
wiley   +1 more source

Inhibition of Low-Density Lipoprotein Oxidation by Cysteamine, Cystamine, Cysteine and Cystine at Lysosomal pH and pH 7.4. [PDF]

Antioxidants (Basel)
Parkes EJ, Cruz AM, Kaur A, Clark GR, Pulford TE, Ness C, Ahmad F, Wen Y, Leake DS.   +8 more
europepmc   +1 more source

Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Have Distinct Prediagnostic Blood Biochemical Profiles

Annals of Neurology, EarlyView.
Objective Identifying modifiable factors influencing amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) risk is important for prevention. Blood biomarkers, particularly cholesterol, have been associated with neurodegenerative risk, but findings in ALS are inconsistent, and data on FTD are limited.
Christos V. Chalitsios, Jiali Gao, Carol A.C. Coupland, Julia Hippisley Cox, Martin R. Turner, Alexander G. Thompson   +5 more
wiley   +1 more source

Opportunistic Genomic Screening for Familial Hypercholesterolemia to Improve Low-Density Lipoprotein Cholesterol: A Randomized Clinical Trial.

JAMA Netw Open
Vassy JL, Brunette CA, Yi T, Assimes TL, Christensen KD, Knowles JW, Sturm AC, Sun YV, Alexander N, Cardellino MP, Harrison A, Gerety HL, Pyatt M, Vered R, Wilson PWF, Natarajan P, Whitbourne SB, Gaziano JM, Muralidhar S, Danowski ME, Veterans Affairs Million Veteran Program.   +20 more
europepmc   +1 more source

Low density lipoprotein receptor-related protein 8: a critical receptor for tick-borne encephalitis virus entry. [PDF]

Signal Transduct Target Ther
Jiao P, Du L, Zeng Y.
europepmc   +1 more source

Effects of Low-Dose Simvastatin on the Distribution of Plasma Cholesterol and Oxidized Low-Density Lipoprotein in Three Ultra-centrifugally Separated Low-Density Lipoprotein Subfractions: 12- Month, Open-Label Trial

, 2010
Yasuhiko Homma, Ichiro Michishita, Hiroshi Hayashi, Hiroshi Shigematsu   +3 more
openalex   +2 more sources

Hydroxycarboxylic Acid Receptor 2 Mediates β‐hydroxybutyrate's Antiseizure Effect in Mice

Annals of Neurology, EarlyView.
A Objective The ketogenic diet, a high‐fat, low‐carbohydrate regimen, is often used to treat drug‐resistant seizures and is being studied for Alzheimer's disease and other neuropsychiatric disorders. However, its mechanism of action remains unclear. β‐hydroxybutyrate, a primary circulating ketone body produced by the ketogenic diet, may mediate its ...
Soudabeh Naderi, John Williamson, Huayu Sun, Suchitra Joshi, Rachel Jane Spera, Savaira Zaib, Supriya Sharma, Chengsan Sun, Andrey Brodovskiy, Ifrah Zawar, Jaideep Kapur   +10 more
wiley   +1 more source

Risk of Retinal Vascular Occlusive Disease According to Type and Low-Density Lipoprotein-Cholesterol Control after Acute Coronary Syndrome. [PDF]

Yonsei Med J
Kim M, Lee JH, Cho YH, Bae K, Lee JY.
europepmc   +1 more source