Results 301 to 310 of about 1,184,339 (384)

Impact of obesity on low density lipoprotein plasmatic levels 6 weeks after an acute coronary syndrome. [PDF]

open access: yesCardiovasc Endocrinol Metab
Bourgeois E   +8 more
europepmc   +1 more source

The Low-Density Lipoprotein Receptor-Related Protein-1 Is Essential for Dengue Virus Infection. [PDF]

open access: yesViruses
Huerta V   +11 more
europepmc   +1 more source

Discordance Between Very Low-Density Lipoprotein Cholesterol and Low-Density Lipoprotein Cholesterol Increases Cardiovascular Disease Risk in a Geographically Defined Cohort. [PDF]

open access: yesJ Am Heart Assoc
Seehusen KE   +11 more
europepmc   +1 more source

Harnessing Viral Proteases for Cellular and Molecular Engineering

open access: yesChemistry–Methods, EarlyView.
Engineered viral proteases (VIPs) provide programmable control of protein function with high specificity and low toxicity. Integrated with chemogenetic and optogenetic modules, these VIP systems enable logic gate manipulation for targeted regulation of cell signaling, gene expression, protein secretion, and degradation, thereby offering versatile ...
Mingguang Cui   +2 more
wiley   +1 more source

Model‐Informed Drug Development Applications and Opportunities in mRNA‐LNP Therapeutics

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The utilization of lipid nanoparticles (LNP) for encapsulating mRNA has revolutionized the field of therapeutics, enabling the rapid development of COVID‐19 vaccines and cancer vaccines. However, the clinical development of mRNA‐LNP therapeutics faces numerous challenges due to their complex mechanisms of action and limited clinical experience.
Jiawei Zhou   +6 more
wiley   +1 more source

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