Results 311 to 320 of about 1,439,975 (404)

Clinical significance of small dense low-density lipoprotein cholesterol measurement in type 2 diabetes. [PDF]

J Diabetes Investig
Hirano T.
europepmc   +1 more source

Optimization of pharmaceutical research and development by early‐phase assessment of investigational medicinal products

British Journal of Clinical Pharmacology, EarlyView.
Small and mid‐sized pharmaceutical innovators often have limited in‐house health economics and market access expertise, and may struggle to align development strategies of investigational medicinal products with health system needs and payer expectations.
Zoltán Kaló, Attila Imre, Gábor Varga, Sándor Kovács, György Tímár, Balázs Nagy   +5 more
wiley   +1 more source

Cardiovascular Outcomes With Icosapent Ethyl by Baseline Low-Density Lipoprotein Cholesterol: A Secondary Analysis of the REDUCE-IT Randomized Trial. [PDF]

J Am Heart Assoc
Aggarwal R, Bhatt DL, Steg PG, Miller M, Brinton EA, Dunbar RL, Ketchum SB, Tardif JC, Martens FMAC, Ballantyne CM, Szarek M, Mason RP, REDUCE‐IT Investigators.   +12 more
europepmc   +1 more source

Genetic data do not provide evidence that lower sclerostin is associated with increased risk of atherosclerosis: comment on the article by Zheng et al

Arthritis &Rheumatology, EarlyView.
James R. Staley, Olga Giannakopoulou, Gill Holdsworth, Martin Armstrong   +3 more
wiley   +1 more source

Use of LC‐MS to characterize host cell protein removal during depth filtration

Biotechnology Progress, EarlyView.
Abstract The removal of host cell proteins (HCPs) is crucial in biopharmaceutical production, as residual impurities can impact product safety and efficacy. While a number of studies have demonstrated that depth filtration can provide significant HCP removal, there is little information on its effectiveness in removing specific HCPs.
Liang‐Kai Chu, Ehsan Espah Borujeni, Xuankuo Xu, Andrew L. Zydney   +3 more
wiley   +1 more source

Effects of Cumulative Low-Density Lipoprotein Cholesterol Exposure on Endothelial Function in Subjects Receiving Lipid-Lowering Drugs. [PDF]

JACC Asia
Yamaji T, Yusoff FM, Kishimoto S, Kajikawa M, Harada T, Mizobuchi A, Tanigawa S, Maruhashi T, Nakashima A, Higashi Y.   +9 more
europepmc   +1 more source

Reply

Arthritis &Rheumatology, EarlyView.
Jie Zheng, George Davey Smith, Jonathan H. Tobias   +2 more
wiley   +1 more source

Neutrophils in cancer: At the crucial crossroads of anti‐tumor and pro‐tumor

Cancer Communications, EarlyView.
Abstract Neutrophils are important components of the immune system and play a key role in defending against pathogenic infections and responding to inflammatory cues, including cancer. Their dysregulation indicates potential disease risk factors. However, their functional importance in disease progression has often been underestimated due to their ...
Wenpeng Cai, Tao Fan, Chu Xiao, Ziqin Deng, Yixiao Liu, Chunxiang Li, Jie He   +6 more
wiley   +1 more source

Impact of Elevated Low-Density Lipoprotein and the Risk of Acute Coronary Syndrome in Rheumatoid Arthritis: A Retrospective Study. [PDF]

Cureus
Sherwani Y, Al-Ezzi S, Thambidorai S.
europepmc   +1 more source