Results 331 to 340 of about 1,184,339 (384)

Low-density lipoprotein and oxidised low-density lipoprotein: Their role in the development of atherosclerosis

Pharmacology & Therapeutics, 1997
Oxidation of low-density lipoprotein (LDL) may be implicated in the development of atherosclerotic disease. Oxidised LDL is taken up more readily by monocyte-derived macrophages than LDL. Antibodies to oxidised LDL are found in atherosclerotic lesions, Increased risk of ischaemic heart disease is associated with a preponderance of small dense LDL ...
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Immunity to Low-Density Lipoprotein [PDF]

, 2011
Animal experiments, epidemiological studies and clinical investigations all show that high levels of plasma low-density lipoprotein (LDL) promote atherosclerotic cardiovascular disease [1]. LDL particles contain epitopes that trigger cellular and humoral immune responses. Autoimmunization during the course of atherosclerosis generates proinflammatory T
Göran K. Hansson, Göran K. Hansson
openaire   +1 more source

Low-Density Lipoprotein Receptor-Related Proteins

Encyclopedia of Molecular Pharmacology, 2021
M. Narita, David M Holtzman, Alan, L., Schwartz, G. Bu   +5 more
semanticscholar   +1 more source

Low-density Lipoproteins in Atherogenesis

2000
It is well established that high levels of plasma cholesterol, particularly those associated with low-density lipoprotein (LDL), increase the risk of developing atherosclerosis. It is also clear that lowering plasma cholesterol levels can arrest or even reverse the progression of the disease [1,2].
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Proteome of human plasma very low-density lipoprotein and low-density lipoprotein exhibits a link with coagulation and lipid metabolism

Thrombosis and Haemostasis, 2014
Summary Apart from transporting lipids through the body, the human plasma lipoproteins very low-density lipoprotein (VLDL) and low-density lipoprotein (LDL) are also thought to serve as a modality for intra-organismal protein transfer, shipping proteins ...
M. Dashty, M. Motazacker, J. Levels, Marcel Vries, Morteza Mahmoudi, M. Peppelenbosch, F. Rezaee   +6 more
semanticscholar   +1 more source

Low density lipoprotein turnover in swine

Canadian Journal of Biochemistry, 1978
The catabolism of intravenously injected 125I-labelled low density lipoproteins (LDL) was followed in normal miniature swine for 2 weeks. When compared with the two-exponential model, the decay curve of the plasma radioactivity associated with the LDL fraction was best described by a three-exponential model. In this system, the half-lives were 4.5 ± 3.
Y.L. Marcel, W. T. Robinson, D. Jeffries, M. Bidallier, M. Bergseth, A.C. Nestruck   +5 more
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Low-density lipoprotein oxidation.

Italian heart journal : official journal of the Italian Federation of Cardiology, 2001
Free radical mediated oxidation of low-density lipoproteins (LDL), which has been extensively studied in the last two decades, plays a central role in the development of the atherosclerotic plaque. Oxidation involves the lipid moiety of LDL in a chain reaction mechanism.
IULIANO, Luigi, MICHELETTA F, VIOLI, Francesco   +2 more
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Is directly measured low-density lipoprotein clinically equivalent to calculated low-density lipoprotein?

Journal of Clinical Lipidology, 2010
Low-density lipoprotein cholesterol (LDL-C) can either be calculated or measured directly. Clinical guidelines recommend the use of calculated LDL-C (C-LDL-C) to guide therapy because the evidence base for cholesterol management is derived almost exclusively from trials that use C-LDL-C, with direct measurement of LDL-C (D-LDL-C) being reserved for ...
Swapna Johnson, Bhanu Gupta, Katelyn Kelly-Johnson, Lawrence Baruch, Lawrence Baruch, Calvin Eng, Calvin Eng, Ann F. Haynos, Sanjay Agarwal   +8 more
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An antibody to low density lipoprotein in diabetics [PDF]

Experientia, 1978
The serum of 21/180 unselected diabetics contains a low titre antibody to human low density lipoprotein. A similar antibody was found in 10/88 persons with tuberculosis.
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Small, dense low-density lipoprotein particles as a predictor of the risk of ischemic heart disease in men. Prospective results from the Québec Cardiovascular Study.

Circulation, 1997
BACKGROUND Case-control studies have reported that patients with ischemic heart disease (IHD) have a higher proportion of small, dense LDL particles than do healthy control subjects.
Benoicirct Lamarche, A. Tchernof, S. Moorjani, B. Cantin, G. Dagenais, P. Lupien, J. Despre´s   +6 more
semanticscholar   +1 more source