Results 341 to 350 of about 1,439,975 (404)
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Clinical Laboratory, 2017
Malondialdehyde low-density lipoprotein (MDA-LDL) is a major form of oxidized LDL and considered to be more atherogenic than LDL. Information on major determinants of MDA-LDL and their association in subjects who are not under treatment for diabetes mellitus and dyslipidemia is limited.This study included 778 Japanese subjects who were not taking ...
Kengo Moriyama, Eiko Takahashi
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Malondialdehyde low-density lipoprotein (MDA-LDL) is a major form of oxidized LDL and considered to be more atherogenic than LDL. Information on major determinants of MDA-LDL and their association in subjects who are not under treatment for diabetes mellitus and dyslipidemia is limited.This study included 778 Japanese subjects who were not taking ...
Kengo Moriyama, Eiko Takahashi
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The low-density lipoprotein pathway and its relation to atherosclerosis.
Annual Review of Biochemistry, 1977PERSPECTIVES AND SUMMARY 898 LDL, THE MAJOR CHOLESTEROL-CARRYING LIPOPROTEIN OF HUMAN PLASMA . 901 Structure of Plasma LDL .. ... .... 901 Origin of Plasma LDL 902 Catabolism of Plasma LDL 902 THE LDL PATHWAY IN HUMAN FIBROBLASTS ..... ...... 903 The LDL
J. Goldstein, M. Brown
semanticscholar +1 more source
Low-density lipoprotein heterogeneity
Baillière's Clinical Endocrinology and Metabolism, 1995As a key feature of the ALP, a raised level of small, dense LDL forms part of what is potentially the most common collection of lipoprotein abnormalities to influence the risk of CHD in the general population. The consistency of the association between a prevalence of small, dense LDL and increased risk of CHD is impressive, though the practical ...
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Low Density Lipoproteins and Hypercholesterolemia
1989Coronary and vascular disease of atherosclerotic origin are the main causes of death and at the same time the most frequent reasons for early invalidity in the Federal Republic of Germany and other industrialized nations. In particular, coronary heart disease (CHD) is the major cause of death in middle-aged men.
H. Funke, G. Assmann, G. Schmitz
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Low-density lipoprotein subclass patterns and risk of myocardial infarction.
Journal of the American Medical Association (JAMA), 1988The association of low-density lipoprotein (LDL) subclass patterns with coronary heart disease was investigated in a case-control study of nonfatal myocardial infarction.
M. Austin +5 more
semanticscholar +1 more source
The low density lipoprotein receptor
Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1989The study of familial hypercholesterolemia at the molecular level has led to its advancement from a clinical syndrome to a fascinating experimental system. FH was first described 50 years ago by Carl Müller who concluded that the disease produces high plasma cholesterol levels and myocardial infarctions in young people, and is transmitted as an ...
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On the metabolic conversion of human plasma very low density lipoprotein to low density lipoprotein
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1973Abstract The relationship of 125I-labelled apoproteins of very low density lipoprotein to that of other lipoproteins was studied in humans during steady-state conditions and following heparin injection. Heterogeneous metabolism of very low density lipo-protein apoproteins in normal individuals was apparent during steady-state conditions ...
Robert I. Levy +3 more
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Cytotoxic Effect of Low-Density Lipoproteins
Bulletin of Experimental Biology and Medicine, 2003The cytopathogenic effect of various modified lipoproteins on cultured peritoneal macrophages was studied in vitro. After minor peroxide modification lipoproteins induced apoptosis of macrophages. Immune complexes containing oxidized lipoproteins caused cell necrosis.
A. N. Voskan'yants +4 more
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Mild autoxidation of low density lipoproteins
Pharmaceutica Acta Helvetiae, 1996The autoxidation of low density lipoproteins was investigated in a closed system, with limited amount of oxygen. The concentrations of several components were monitored: oxygen, aldehydic oxidation products and alpha-tocopherol. The concentration of lipid radicals generated in the processes of lipid peroxidation was monitored by the EPR spin trapping ...
Tatjana Ukrainczyk +2 more
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Atherosclerosis, 1995
We have identified two familial defective apo B-100 (FDB) homozygotes by DNA sequencing and have measured affinity of low-density lipoproteins (LDL) and very-low-density lipoprotein (VLDL) remnants for the LDL receptor in vitro. The patients were a 66-year-old man with coronary heart disease (plasma cholesterol level, 9.5 mmol/l before treatment) and ...
John J. Gallagher, Nicolas B. Myant
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We have identified two familial defective apo B-100 (FDB) homozygotes by DNA sequencing and have measured affinity of low-density lipoproteins (LDL) and very-low-density lipoprotein (VLDL) remnants for the LDL receptor in vitro. The patients were a 66-year-old man with coronary heart disease (plasma cholesterol level, 9.5 mmol/l before treatment) and ...
John J. Gallagher, Nicolas B. Myant
openaire +2 more sources