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An antibody to low density lipoprotein in diabetics [PDF]
The serum of 21/180 unselected diabetics contains a low titre antibody to human low density lipoprotein. A similar antibody was found in 10/88 persons with tuberculosis.
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The Low-Density Lipoprotein Receptor
1987The low-density lipoprotein (LDL) receptor is a prototype for a class of cell surface receptors that bind lipoproteins and other circulating macromolecules and carry them into cells by receptor-mediated endocytosis. The human LDL receptor is a single-chain transmembrane glycoprotein of 839 amino acids.
Joseph L. Goldstein, Michael S. Brown
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Desialylated low density lipoproteins and atherosclerosis
1992Oxidative modification of LDL is accompanied by a number of compositional and structural changes, now well known. In addition, other atherogenic modifications of LDL exist, such as desialylation. The present article summarizes the recent data related to desialylated LDL and to the presence of these LDL in blood plasma of patients with coronary ...
Marie Laure Solera M.D.+3 more
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Lipoprotein Metabolism: Chylomicrons, Very-Low-Density Lipoproteins and Low-Density Lipoproteins [PDF]
Audra V. Lembertas, Verne N. Schumaker
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The catabolism of very low density lipoproteins
Canadian Journal of Biochemistry and Cell Biology, 1985The lipolysis of very low density lipoproteins (VLDL) in vitro is a useful model for the study of the process of conversion of this triacylglycerol rich lipoprotein into low (LDL) and high (HDL) density lipoproteins. Data is reviewed to show that a portion of surface cholesterol and phospholipid which becomes redundant during lipolysis is lost from ...
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Mammalian Low Density Lipoproteins
1976During the past few years considerable advances have been made in the study of mammalian plasma low density lipoproteins. Although human LDL is of prime interest, mainly because of its association with atherosclerosis, many studies can most satisfactorily be carried out on animals, including work on the mechanisms of LDL production and metabolism, the ...
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Oxidised Low Density Lipoproteins
1993The evidence for the oxidative modification of low density lipoprotein (LDL) and its subsequent recognition by the scavenger receptors on macrophages in vitro is clear. The presence of oxidatively modified LDL in atherosclerotic lesions is well-recognised. However, the mechanism whereby LDL becomes oxidised in vivo is yet to be clarified.
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