Results 91 to 100 of about 601,516 (329)

Effects of Wet Cupping (Al-Hijamah) on Cholesterol in a Sudanese Population

Journal of Acupuncture Research, 2023
Background: Wet cupping (WC) is an efficient and cost-effective technique for removing metabolic waste from the bloodstream via the skin. The study aimed to examine the effect of WC on cholesterol levels including total cholesterol (TC), high-density ...
Amna Mohammed Alamin Abbshar, Hafsa Ahmed Elrheima Ahmed   +1 more
doaj   +1 more source

Recombinant Incretin-Secreting Microbe Improves Metabolic Dysfunction in High-Fat Diet Fed Rodents [PDF]

, 2017
peer-reviewedThe gut hormone glucagon-like peptide (GLP)-1 and its analogues represent a new generation of anti-diabetic drugs, which have also demonstrated propensity to modulate host lipid metabolism.
Cryan, John F., Dinan, Timothy G., Kent, Robert M., Mandal, Rupasri, Murphy, Kiera, O’Connor, Paula M., Patterson, Elaine, Peterson, Veronica L., Ross, R Paul, Ryan, Paul M, Seeley, Randy J., Stack, Helena, STANTON, CATHERINE, Wishart, David S.   +13 more
core   +5 more sources

Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review

BMJ Open, 2016
Objective It is well known that total cholesterol becomes less of a risk factor or not at all for all-cause and cardiovascular (CV) mortality with increasing age, but as little is known as to whether low-density lipoprotein cholesterol (LDL-C), one ...
U. Ravnskov, D. Diamond, Rokura Hama, T. Hamazaki, B. Hammarskjöld, N. Hynes, M. Kendrick, P. Langsjoen, Aseem Malhotra, L. Mascitelli, K. Mccully, Y. Ogushi, H. Okuyama, P. Rosch, T. Scherstén, S. Sultan, Ralf Sundberg   +16 more
semanticscholar   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source

Atherogenic Lipoprotein Determinants of Cardiovascular Disease and Residual Risk Among Individuals With Low Low‐Density Lipoprotein Cholesterol

Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease, 2017
Background Levels of LDL (low‐density lipoprotein) cholesterol in the population are declining, and increasing attention is being focused on residual lipid‐related pathways of atherosclerotic cardiovascular disease risk beyond LDL cholesterol.
P. Lawler, A. Akinkuolie, Audrey Y. Chu, Svati H. Shah, W. Kraus, D. Craig, Latha Padmanabhan, R. Glynn, P. Ridker, D. Chasman, S. Mora   +10 more
semanticscholar   +1 more source

Skeletal Muscle HSF1 Alleviates Age‐Associated Sarcopenia and Mitochondrial Function Decline via SIRT3‐PGC1α Axis

Advanced Science, EarlyView.
Aged HSF1 muscle‐specific knockout mice show deteriorated muscle atrophy and metabolic dysfunction, while active HSF1 overexpression improves muscle function via activating SIRT3 to deacetylate both PGC1α1 and PGC1α4, which boosts mitochondrial function and muscle hypertrophy in a fiber‐type specific manner, and induces FNDC5/Irisin for tissue ...
Jun Zhang, Min Hu, Xia Wu, Mingwei Guo, Ying Ma, Jin Qiu, Siqi Wang, Yuxiang Cao, Yinzhao Zhong, Fangfang Chen, Yiwen Wang, Wei Wei, Yan Lu, Yong Zhang, Junjie Xiao, Zhenji Gan, Cheng Hu, Xinran Ma, Lingyan Xu   +18 more
wiley   +1 more source

Metabolic effects of berberine on liver phosphatidate phosphohydrolase in rats fed on high lipogenic diet: An additional mechanism for the hypolipidemic effects of berberine [PDF]

, 2014
Objective: To evaluate the effects of berberine (BBR) on the liver phosphatidate phosphohydrolase (PAP) and plasma lipids in rats fed on high lipogenic and normal diet. Methods: Forty rats were randomly divided into 5 groups.
Bakhshesh, M., Heidarian, E., Khoshdel, A., Rafieian-Kopaei, M.   +3 more
core  

Pathophysiology of elevated ascites fluid cholesterol in malignant ascites [PDF]

, 1992
The existence of marked elevations of ascitic fluid cholesterol has been observed in patients with peritoneal carcinomatosis compared to patients with cirrhosis and has been found useful in differential diagnosis.
Alexander L. Gerbes, Caselmann, Conrad, Dieter Jüngst, Garrison, Gerbes, Henderson, Henriksen, Hirabayashi, Hoefs, Hoefs, Jüngst, Kerscher, Lifshitz, Loiudice, Lopes-Virella, Mortensen, Pare, Polak, Prieto, Romette, Rovelstad, Röschlau, Suzuki, Weichselbaum, Weisweiler, Witte, Yining Xie   +27 more
core   +1 more source

Association Between Low-Density Lipoprotein Cholesterol Levels and Risk for Sepsis Among Patients Admitted to the Hospital With Infection

JAMA Network Open, 2019
Key Points Question What is the association between low levels of low-density lipoprotein cholesterol and risk of sepsis in patients admitted to the hospital with serious infection? Findings In this cohort study of deidentified electronic medical records
Q. Feng, Wei-Qi Wei, Sandip Chaugai, Barbara G. Carranza Leon, Jonathan Mosley, Daniel A. Carranza Leon, Lan Jiang, Andrea Ihegword, Christian M. Shaffer, MacRae F. Linton, Cecilia P Chung, C. M. Stein   +11 more
semanticscholar   +1 more source

Postoperative Stress Accelerates Atherosclerosis Through Inflammatory Remodeling of the HDL Proteome and Impaired Reverse Cholesterol Transport

Advanced Science, EarlyView.
The study shows that noncardiac surgical inflammation rapidly disrupts HDL function and cholesterol efflux in mice and human patients. Impaired reverse cholesterol transport after surgery drives rapid lipid accumulation, NETosis, and apoptosis within atherosclerotic plaques.
Dominique M. Boucher, Victoria Lorant, Valerie Rochon, Abigail Carter, Cameron Stotts, My‐Anh Nguyen, Thomas Laval, Christina Emerton, Nathan Joyce, Nysa Vinayak, Marlena Scaffidi, David Cook, Katey J. Rayner, Rebecca C. Auer, Scott M. Gordon, Mireille I. Ouimet   +15 more
wiley   +1 more source