Results 111 to 120 of about 601,516 (329)

Evaluation of alteration in serum lipid levels in patients with chronic periodontitis postperiodontal therapy

Journal of Indian Academy of Oral Medicine and Radiology, 2011
Aim: There is growing evidence that periodontitis may affect general health. This study was assigned to explore changes in cholesterol levels following nonsurgical periodontal therapy in patients with chronic periodontitis.
Vivek N Thombre, Aparna Sharma Thombre, Manohar L Bhongade, R M Zade, Praveen Sundarkar, Shailesh Gondivkar   +5 more
doaj   +1 more source

Which lipid measurement should we monitor? An analysis of the LIPID study [PDF]

, 2014
OBJECTIVES: To evaluate the optimal lipid to measure in monitoring patients, we assessed three factors that influence the choice of monitoring tests: (1) clinical validity; (2) responsiveness to therapy changes and (3) the size of the long-term ‘signal ...
Glasziou, Paul P., Irwig, Les, Kirby, Adrienne C., Simes, R. John, Tonkin, Andrew M.   +4 more
core   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Small dense low‐density lipoprotein cholesterol is a promising biomarker for secondary prevention in older men with stable coronary artery disease

Geriatrics & Gerontology International, 2018
The study objective was to investigate whether small dense low‐density lipoprotein cholesterol (sdLDL‐C) is superior to low‐density lipoprotein cholesterol (LDL‐C) and other biomarkers to predict future cardiovascular events (CE) in secondary prevention.
K. Sakai, S. Koba, Yuya Nakamura, Yuya Yokota, Fumiyoshi Tsunoda, Makoto Shoji, Yasuki Itoh, Yuji Hamazaki, Youichi Kobayashi   +8 more
semanticscholar   +1 more source

APOE‐stratified Proteomic and Metabolomic Analysis Reveals Mitochondrial Dysfunction Inflammation and Lipid Dysregulation in Alzheimer's Disease

Advanced Science, EarlyView.
A large‐scale multiomic dataset (proteomic and metabolomic) comprising 3,060 plasma samples were analyzed to identify proteins, metabolites, pathways, and protein‐associated drugs linked to Alzheimer’s Disease (AD) independently of apolipoprotein E (APOE). AD was associated with a distinct molecular signature that captures.
Fuhai Li, Yike Chen, Daniel Western, Muhammad Ali, Menghan Liu, Katherine Gong, Ying Xu, Joseph Lowery, David M. Holtzman, Chloe Robins, John D. Eicher, Yen‐Ning Huang, ShiWei Liu, Tamina Park, Andrew J. Saykin, Kwangsik Nho, Mahdi Moqri, Richard C. Mohs, Amelia Farinas, Patricia Moran‐Losada, Hamilton Se‐Hwee Oh, Tony Wyss‐Coray, Carlos Cruchaga   +22 more
wiley   +1 more source

Should We Forget About Low-Density Lipoprotein Cholesterol?

Journal of the American College of Cardiology, 2014
The U.S. National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults recommendations [(1)][1] have had a huge impact on the treatment of hypercholesterolemia around the world and have had a decisive influence on ...
Civeira, Fernando, Ascaso, Juan, Masana, Luis   +2 more
openaire   +2 more sources

Contribution and interaction of the low‐density lipoprotein cholesterol to high‐density lipoprotein cholesterol ratio and triglyceride to diabetes in hypertensive patients: A cross‐sectional study

Journal of Diabetes Investigation, 2018
Hypertension is one of the most significant risk factors for diabetes. The present study aimed to investigate the associations of lipid profiles, including the ratio of low‐density lipoprotein cholesterol (LDL‐C)‐to‐high‐density lipoprotein cholesterol ...
M. Hong, Y. Ling, Zhiqiang Lu, Y. Liu, P. Gu, J. Shao, Xin Gao, Xiaomu Li   +7 more
semanticscholar   +1 more source

In Situ Lipoprotein‐seeking Dye for in Vivo Real‐Time Imaging of Lipid Dysregulation Diseases

Advanced Science, EarlyView.
This study develops lipoprotein‐seeking NIR‐II dyes that specifically bind circulating lipoproteins. These dyes form ultra‐stable complexes with endogenous lipoprotein, enabling real‐time, high‐contrast imaging of fatty liver and atherosclerotic plaques. Tunable binding kinetics allow customized imaging windows.
Yijing Du, Zetao Dang, Baofeng Xu, Jiajun Xu, Dan Wang, Yuewei Zhang, Shoujun Zhu   +6 more
wiley   +1 more source

Effect of raw and heated flaxseed (Linum usitatissimum L.) on blood lipid profiles in rats. [PDF]

, 2011
Flaxseed is a nutrient rich seed and lipid profiles improving effect of it has long been studied. Effect of heating as a part of food processing on its beneficial characteristics is not clarified in literature.
Ismail, Amin, Jamaluddin, Rosita, Khalesi, Saman   +2 more
core   +1 more source

Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells [PDF]

, 2019
Pancreatic β-cells are sensitive to fluctuations in cholesterol content, which can damage the insulin secretion pathway, contributing to the aetiology of type 2 diabetes mellitus.
Caridis, Anna Maria, Dolan, Sharron, Graham, Annette, Lightbody, Richard J., Tarlton, Jamie M.R.   +4 more
core   +1 more source