Results 71 to 80 of about 601,516 (329)

Comparison of Low-Density Lipoprotein Cholesterol Assessment by Martin/Hopkins Estimation, Friedewald Estimation, and Preparative Ultracentrifugation: Insights From the FOURIER Trial

JAMA cardiology, 2018
Importance Recent studies have shown that Friedewald underestimates low-density lipoprotein cholesterol (LDL-C) at lower levels, which could result in undertreatment of high-risk patients.
S. Martin, R. Giugliano, S. Murphy, S. Wasserman, E. Stein, R. Češka, J. López-Miranda, B. Georgiev, A. Lorenzatti, M. Tikkanen, P. Sever, A. Keech, T. Pedersen, M. Sabatine   +13 more
semanticscholar   +1 more source

Response to Allopurinol and Febuxostat According to the Fractional Excretion of Urate in Men With Gout

Arthritis Care &Research, EarlyView.
Objective Body mass index (BMI), glomerular filtration rate (GFR), and pretreatment urate levels have been reported to influence the urate‐lowering response to allopurinol. We investigated whether the fractional excretion of uric acid (FEUA) also modulates this response and relates to oxypurinol concentrations.
Pascal Richette, Anouk Walter‐Petrich, Quang Dinh Nguyen, Matthieu Resche‐Rigon, Quang Huy Dinh Nguyen, Minh Duc Do, Thao Phuong Mai, Tuan Duc Nguyen, Fernando Perez‐Ruiz, Emmanuel Letavernier, Tristan Pascart, Augustin Latourte, Hang Korng Ea, Thomas Bardin   +13 more
wiley   +1 more source

Antiatherogenic Potential of Transcranial Electrical Stimulation in a High-Fructose/High-Fat Diet: Experimental Randomized Trial

Кубанский научный медицинский вестник, 2023
Background. Transcranial electrical stimulation is a promising method for correction of malnutrition-induced hyperlipidemia, in the absence of indications for drug hypolipidemic therapy in young and middle-aged patients with low and moderate ...
E. A. Chabanets, A. Kh. Kade, A. I. Trofimenko, G. G. Kim, V. A. Krutova   +4 more
doaj   +1 more source

Estimation of serum lipids in patients with Oral Submucous Fibrosis in India [PDF]

, 2014
Objectives: Oral submucous fibrosis (OSMF) is the most prevalent precancerous condition in India. Low levels of lipids serves as a marker and prognostic indicator in the early detection of oral precancerous and cancerous states.
Agarwal, Nupur, Aggarwal, Ashish, Ajai, Kratika, Joshi, Anuja, Panat, Sunil R., Upadhyay, Nitin   +5 more
core   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Baseline and follow-up change of cholesterol levels predict dementia risk and progression in older adults: a U-shaped relationship

Alzheimer’s Research & Therapy
Introduction Previous studies on serum lipid levels and cognitive outcomes have shown inconsistent results, partly due to differences in timing of lipid assessment, cognitive status, and lack of longitudinal data.
Pai-Yi Chiu, Hsi-Hsien Chou, Chih-Li Lin, Hsin-Hua Li, Tzu-Yu Chen, Hong-Ming Chen, Hsin-Te Chang   +6 more
doaj   +1 more source

Biological, clinical and population relevance of 95 loci for blood lipids. [PDF]

, 2010
Plasma concentrations of total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol and triglycerides are among the most important risk factors for coronary artery disease (CAD) and are targets for therapeutic ...
Aulchenko, Yurii S, Barbalic, Maja, Bis, Joshua C, Chambers, John, Chasman, Daniel I, Croteau-Chonka, Damien C, Edmondson, Andrew C, Feitosa, Mary F, Fouchier, Sigrid W, Guo, Xiuqing, Hua Zhao, Jing, Isaacs, Aaron, Jin Go, Min, Jin Kim, Young, Johansen, Christopher T, Johnson, Toby, Kim, Kyunga, Koseki, Masahiro, Lamina, Claudia, Lange, Leslie A, Lee, Jong-Young, Li, Mingyao, Li, Xiaohui, Luan, Jian'an, McCarthy, Mark I, McPherson, Ruth, Meitinger, Thomas, Melander, Olle, Montgomery, Grant W, Musunuru, Kiran, Nickerson, Deborah A, Nieminen, Markku S, O'Donnell, Christopher J, Oostra, Ben A, Orho-Melander, Marju, Pare, Guillaume, Park, Taesung, Parker, Alex N, Pattaro, Cristian, Pedersen, Nancy L, Peloso, Gina M, Penninx, Brenda WJH, Perola, Markus, Pichler, Irene, Pirruccello, James P, Pramstaller, Peter P, Psaty, Bruce M, Ricketts, Sally L, Rieder, Mark, Ripatti, Samuli, Roberts, Robert, Rose, Lynda M, Rudan, Igor, Ruokonen, Aimo, Sabatti, Chiara, Saharinen, Juha, Salomaa, Veikko, Sanna, Serena, Schlessinger, David, Scott, James, Scuteri, Angelo, Shin Cho, Yoon, Sijbrands, Eric JG, Silander, Kaisa, Sim, Xueling, Sinisalo, Juha, Smit, Johannes H, Smith, Albert V, Smith, Joshua D, Song, Kijoung, Soranzo, Nicole, Spector, Tim D, Stringham, Heather M, Stylianou, Ioannis M, Surakka, Ida, Tanaka, Toshiko, Teslovich, Tanya M, Thompson, John R, Thorleifsson, Gudmar, Tuomilehto, Jaakko, Twee-Hee Ong, Rick, Uda, Manuela, Uitterlinden, Andre G, Vitart, Veronique, Voight, Benjamin F, Vollenweider, Peter, Waeber, Gérard, Wareham, Nicholas J, Waterworth, Dawn M, Whitfield, John B, Wichmann, H-Erich, Willemsen, Gonneke, Willer, Cristen J, Wilson, James F, Witteman, Jacqueline CM, Wright, Alan F, Yuan, Xin, Zee, Robert YL, Zhang, Weihua, Ziegler, Andreas   +99 more
core  

Effect of kelussia odoratissima mozaffarian on lipid and glucose profile [PDF]

, 2015
Background: Flavonoids are a group of polyphenolic compounds with antioxidant properties that help reduce cardiovascular risk factors. Kelussia odoratissima is a flavonoid-containing plant, the effect of which was analyzed on decreasing blood lipid ...
Abedi Gheshlaghi, Zahra., Asgari, Azam., Nasri, Parto., Parvin, Neda., Rafieian-Kopaei, Mahmoud., Shahrani, Mehrdad., shirzad, Hedayatollah.   +6 more
core   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source

Thinking beyond low-density lipoprotein cholesterol: strategies to further reduce cardiovascular risk

Vascular Health and Risk Management, 2009
Rakesh K Sharma1, Vibhuti N Singh2, Hanumanth K Reddy11Medical Center of South Arkansas, El Dorado, University of Arkansas for Medical Sciences, Little Rock, AR, USA; 2Bayfront Medical Center, University of South Florida, St. Petersburg, FL, USAAbstract:
Rakesh K Sharma, Vibhuti N Singh, Hanumanth K Reddy   +2 more
doaj