Results 71 to 80 of about 659,039 (264)
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
What's Next for Low-Dimensional Materials? [PDF]
I start this perspectives article with a brief historical review about how graphene logically fits into the nanoscience field from my own perspective in contrast to the actual history of graphene r...
openaire +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Recently, near-infrared (NIR) circularly polarized luminescence (CPL) has emerged as a research hotspot owing to its unique application prospects. Atomic precision Au clusters (AuCs) have shown excellent biocompatibility and characteristic emission in ...
Xichen Hao +14 more
doaj +1 more source
In this paper, magnetically tunable random lasing from a polymer dispersed liquid crystal (PDLC) in a capillary was achieved by means of doping with magnetic nanoparticles (MNPs).
H. T. Dai +8 more
doaj +1 more source
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Nucleotide detection mechanism and comparison based on low-dimensional materials: A review. [PDF]
Azeem MM +5 more
europepmc +1 more source
Integrated Four-Wavelength DFB Diode Laser Array for Continuous-Wave THz Generation
We demonstrate a four-wavelength distributed feedback (DFB) diode laser array integrated with a semiconductor optical amplifier (SOA) for widely tunable terahertz (THz) mode-beating generation. The InP-based monolithically integrated chip consists of DFB
Mengdie Sun +12 more
doaj +1 more source

