Results 71 to 80 of about 659,039 (264)

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

What's Next for Low-Dimensional Materials? [PDF]

open access: yesMaterials Research Letters, 2013
I start this perspectives article with a brief historical review about how graphene logically fits into the nanoscience field from my own perspective in contrast to the actual history of graphene r...
openaire   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

Controllable Fabrication of Vertical Graphene with Tunable Growth Nature by Remote Plasma-Enhanced Chemical Vapor Deposition

open access: yesACS Omega, 2023
Tian-Tian Zhang   +7 more
doaj   +1 more source

Dual-band high-dissymmetry circularly polarized luminescence from cholesteric liquid crystals overlaid a gold cluster film

open access: yesNature Communications
Recently, near-infrared (NIR) circularly polarized luminescence (CPL) has emerged as a research hotspot owing to its unique application prospects. Atomic precision Au clusters (AuCs) have shown excellent biocompatibility and characteristic emission in ...
Xichen Hao   +14 more
doaj   +1 more source

Magnetically tunable random lasing from polymer dispersed liquid crystal doped ferromagnetic nanoparticles in capillary

open access: yesAIP Advances, 2019
In this paper, magnetically tunable random lasing from a polymer dispersed liquid crystal (PDLC) in a capillary was achieved by means of doping with magnetic nanoparticles (MNPs).
H. T. Dai   +8 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Nucleotide detection mechanism and comparison based on low-dimensional materials: A review. [PDF]

open access: yesFront Bioeng Biotechnol, 2023
Azeem MM   +5 more
europepmc   +1 more source

Integrated Four-Wavelength DFB Diode Laser Array for Continuous-Wave THz Generation

open access: yesIEEE Photonics Journal, 2016
We demonstrate a four-wavelength distributed feedback (DFB) diode laser array integrated with a semiconductor optical amplifier (SOA) for widely tunable terahertz (THz) mode-beating generation. The InP-based monolithically integrated chip consists of DFB
Mengdie Sun   +12 more
doaj   +1 more source

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