Results 111 to 120 of about 20,287 (301)

AS‐pHopt: An Optimal pH Prediction Model Enhanced by Active Site of Enzymes

open access: yesAdvanced Intelligent Discovery, EarlyView.
To address the low accuracy of enzyme optimal pH (pHopt) prediction, this study develops active site‐based pHopt (AS‐pHopt), a prediction model enhanced by active site information and pseudo‐label prediction. Integrating key structural and physicochemical features affecting enzyme pHopt, AS‐pHopt uses Evolutionary Scale Modeling (ESM)‐2 with active ...
Wenxiang Song   +6 more
wiley   +1 more source

Printed Wearable Sweat Rate Sensor for Continuous In Situ Perspiration Measurement

open access: yesAdvanced Intelligent Systems, Volume 7, Issue 3, March 2025.
A wireless wearable sweat rate sensor system is presented, featuring digital 3D direct‐write printing on a flexible substrate with microfluidic layers for continuous, real‐time monitoring. Printed encapsulated metal electrodes are used for capacitance measurements, achieving high sensitivity (0.01 μL min−1) while maintaining a compact and lightweight ...
Mohammad Shafiqul Islam   +6 more
wiley   +1 more source

A Generalizable Transformer Framework for Gene Regulatory Network Inference from Single‐Cell Transcriptomes

open access: yesAdvanced Intelligent Systems, EarlyView.
FTGRN introduces an LLM‐enhanced framework for gene regulatory network inference through a two‐stage workflow. It combines a Transformer‐based model, pretrained on GPT‐4 derived gene embeddings and regulatory knowledge, with a fine‐tuning stage utilizing single‐cell RNA‐seq data.
Guangzheng Weng   +7 more
wiley   +1 more source

Autonomous Robotic Colonoscopy: A Supervised Learning Approach for Enhanced Navigation and Collision Detection

open access: yesAdvanced Intelligent Systems, EarlyView.
A novel autonomous robotic colonoscopy is introduced through supervised learning approaches. The proposed system consists of 3 degrees of freedom motorized colonoscope with an integrated navigation module that can infer a target steering point and collision probability.
Bohyun Hwang   +3 more
wiley   +1 more source

Adaptive Autonomy in Microrobot Motion Control via Deep Reinforcement Learning and Path Planning Synergy

open access: yesAdvanced Intelligent Systems, EarlyView.
This study introduces a data‐driven framework that combines deep reinforcement learning with classical path planning to achieve adaptive microrobot navigation. By training a surrogate neural network to emulate microrobot dynamics, the approach improves learning efficiency, reduces training time, and enables robust real‐time obstacle avoidance in ...
Amar Salehi   +3 more
wiley   +1 more source

Designing Low Dropout Regulator with Low Settling Time, High Power Supply Rejection and Low Line and Load Regulation

open access: yesMajlesi Journal of Electrical Engineering
Low dropout regulators are one of the most important factures of many portable devices. Thus, consider to the complexity of the circuits and increasing request for portable devices, for increasing battery life and minimizing supply noise, regulators with
Najmeh Khanian, Abbas Golmakani
doaj  

A community‐driven approach to address substance use and create a Great Plains American Indian addiction and recovery research agenda

open access: yesAmerican Journal of Community Psychology, EarlyView.
Abstract Substance use, specifically opioid and methamphetamine use, is of increasing concern among American Indian (AI) populations in the Great Plains. This community‐driven participatory study investigated the impacts of substance use and community‐defined needs in treating addiction.
Brynn Luger   +8 more
wiley   +1 more source

Efficient LDO-Assisted DC/DC buck converter for integrated power management system [PDF]

open access: yes, 2016
DC-DC Switching Converters; Voltage Linear Regulators; Linear-Assisted DC-DC Voltage Regulators.Postprint (published ...
Martínez García, Herminio
core  

Miniaturized Conductometric Biosensor for Rapid Detection of TNF‐α in Saliva

open access: yesAdvanced NanoBiomed Research, EarlyView.
A miniaturized conductometric sensor detects TNF‐α at femtomolar levels with high selectivity. The device enables noninvasive testing using pooled human saliva and supports smartphone‐based, real‐time resistance readings. This portable biosensor offers a practical alternative for monitoring TNF‐α, providing new opportunities for diabetes and related ...
Mingjie Yang   +8 more
wiley   +1 more source

A Metabolomic Signature Predicts Gout Flare Clinical Outcome Associated With Colchicine Prophylaxis

open access: yesArthritis &Rheumatology, EarlyView.
Objective This study investigated that serum metabolomics, before urate‐lowering therapy (ULT) initiation, could serve as a biomarker for responsiveness to colchicine prophylaxis in patients with gout commencing treat‐to‐target ULT. Methods We studied a multicenter prospective cohort (n = 409) initiating treat‐to‐target ULT plus colchicine prophylaxis.
Wenyan Sun   +13 more
wiley   +1 more source

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