Results 121 to 130 of about 9,037,523 (220)

Paradoxical Normal‐Flow Aortic Stenosis Despite Reduced Left Ventricular Ejection Fraction: Insights From the Randomized COMPARE‐TAVI 1 Trial

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The hemodynamic profile and remodeling patterns of paradoxical low‐flow, low‐gradient aortic stenosis are well understood. However, some patients with severe aortic stenosis exhibit eccentric remodeling with enlarged left ventricular cavities,
Emil Johannes Ravn, Ulrik Christiansen, Henrik Nissen, Jonas Agerlund Povlsen, Christian Alcaraz Frederiksen, Steen Hvitfelt Poulsen, Marie‐Annick Clavel, Rasmus Carter‐Storch, Christian Byskov Fur, Troels Thim, Philip Freeman, Frederik Uttenthal, Evald Høj Christiansen, Christian Juhl Terkelsen, Jordi Sanchez Dahl   +14 more
doaj   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Standardized Reporting of Cardiac Magnetic Resonance Examinations in Children With Cardiac Diseases and Adults With Congenital Heart Disease: A Scientific Statement From the Association for European Pediatric and Congenital Cardiology (AEPC) and the International Society for Magnetic Resonance in Medicine (ISMRM)

Journal of Magnetic Resonance Imaging, EarlyView.
Francesca Raimondi, Inga Voges, Lamia Ait‐Ali, Sonya Babu‐Narayan, Rene Botnar, Barbara Burkhardt, Adrienne Campbell‐Washburn, Dominik Daniel Gabbert, Georg Hansmann, Willem A. Helbing, Hasan Hosan, Sylvia Krupickova, Heiner Latus, Duarte Martins, Colin McMahon, Christian Meierhofer, Vivek Muthurangu, Tiina Ojala, Pim van Ooij, Claudia Prieto, Milan Prsa, Kuberan Pushparajah, José F. Rodríguez Palomares, Samir Sarikouch, Lars Grosse‐Wortman, F. Gerald Greil, Heynric Grotenhuis   +26 more
wiley   +1 more source

Beat‐to‐beat variability of ventricular repolarization reveals sex‐specific instability and proarrhythmic risk

The Journal of Physiology, EarlyView.
Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato, Lorenzo Santini, Raffaele Coppini, Eleonora Grandi   +3 more
wiley   +1 more source

Deep Learning‐Based Dynamic Segmentation of the Left Atrium in 4D Flow MRI

Magnetic Resonance in Medicine, Volume 96, Issue 5, Page 2505-2515, November 2026.
ABSTRACT Purpose To design a deep learning pipeline for automated, time‐resolved segmentation of the left atrium (LA) from 4D flow MRI data. Methods We studied 100 individuals including 65 patients with atrial fibrillation (AF) and 35 healthy subjects (HS) resulting in 2530 4D flow MRI time‐volumes acquired in different centers and scanners.
Jonas Leite, Tom Da‐Silva Faria, Marie Shannon Soulez, Khaoula Bouazizi, Perrine Marsac, Elie Mousseaux, Jérôme Lamy, Moussa Gueda Moussa, Olivier Piot, Jacques Feignoux, Daniel Giese, Nicolas Badenco, Estelle Gandjbakhch, Alban Redheuil, Mikaël Laredo, Emilie Bollache, Nadjia Kachenoura   +16 more
wiley   +1 more source

Postprandial Changes in Thoracic Aortic Flow Detected by 4D Flow MRI May Influence Study Results

Journal of Magnetic Resonance Imaging, Volume 64, Issue 4, Page 898-905, October 2026.
ABSTRACT Background While there is a growing body of data using 4D flow MRI to distinguish between normal and abnormal blood flow values in the thoracic aorta, the extent of physiological variation or lack thereof is potentially undervalued. Physiological processes such as postprandial changes to hemodynamics might influence data, normal values, follow‐
Maren Friederike Balks, Luisa Quest, Andreas Stroth, Alexander Reiber, Patricia Ulloa, Nicolas Kirschke, Malte Maria Sieren, Joachim Graessner, Hendrik Kooijman, Jörg Barkhausen, Alex Frydrychowicz, Thekla Helene Oechtering   +11 more
wiley   +1 more source

Inconsistency of Hemodynamic Data in Low-Gradient Severe Aortic Stenosis

Journal of the American College of Cardiology, 2016
The recently published meta-analysis by Dayan et al. [(1)][1] in the Journal evaluated the outcome and survival impact of aortic valve replacement in patients with low-gradient severe aortic stenosis (AS) in patients with preserved left ventricular ejection fraction, including paradoxical low ...
openaire   +2 more sources

Neutrophil Extracellular Traps in Atherosclerosis and Cardiovascular Disease

MedComm, Volume 7, Issue 10, October 2026.
NETs as integrated effectors in the atherosclerotic cardiovascular disease continuum. Activated neutrophils release NETs that promote endothelial injury, thrombo‐inflammation, and plaque destabilization throughout atherosclerotic disease progression. Created with BioRender.com.
Ji Zhang, Fangjiaqi Wei, Mengdi Qu, Yuwen Shao, Tingye Xu, Darko Stojkov, Hans‐Uwe Simon, Ben Huang, Changhong Miao, Hao Zhang   +9 more
wiley   +1 more source

Fourier Shell Analysis: k‐Space‐Based Metrics for Assessing Super‐Resolution in 4D Flow MRI

Magnetic Resonance in Medicine, Volume 96, Issue 4, Page 1983-1990, October 2026.
ABSTRACT Purpose To support the emerging field of super‐resolution (SR) in 4D flow MRI by proposing Fourier shell analysis to disentangle resolution enhancement from denoising effects during evaluation. Methods A thoracic aortic 4D flow MRI dataset was synthesized with various degrees of stenosis, providing ground truth flow fields generated using ...
Luuk Jacobs, Pietro Dirix, Sebastian Kozerke   +2 more
wiley   +1 more source

Mitochondrial Fusion and Fission in Age‐Related Cardio‐Cerebral Diseases: Mechanisms and Interventions

Aging Cell, Volume 25, Issue 10, October 2026.
Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley   +1 more source