Results 51 to 60 of about 308,273 (354)

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

The Effects of Pre and Post Exercise Low-Level Laser Therapy on Biochemical Markers of Skeletal Muscle Fatigue in Equines [PDF]

, 2019
Our objective was to determine whether administering low-level laser therapy before or after exercise had the greatest effect on biochemical markers of skeletal muscle fatigue in equines such as cortisol and blood lactate.
Freeman, Carson
core   +2 more sources

Pain-motor integration in the primary motor cortex in Parkinson's disease [PDF]

, 2017
In Parkinson's disease (PD), the influence of chronic pain on motor features has never been investigated. We have recently designed a technique that combines nociceptive system activation by laser stimuli and primary motor cortex (M1) activation through ...
Berardelli, Alfredo, Biasiotta, A, Cruccu, Giorgio, Di Santo, A, DI STASIO, Flavio, LA CESA, Silvia, Leone, Caterina, Marsili, Luca, Suppa, Antonio, Truini, Andrea   +9 more
core   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Low- level laser: cost of therapy fornipple trauma

Revista Brasileira de Saúde Materno Infantil
Objectives: to measure the micro-cost of local laser therapy (LL) and transcutaneous laser therapy application by Irradiation Laser Intravascular of Blood (ILIB) to treat nipple trauma and compare the most effective and efficient alternative treatment ...
Danielly Negrão Guassú Nogueira, Franciane Maria da Silva Curan, Alexandrina Aparecida Maciel Cardelli, Rosângela Aparecida Pimenta Ferrari, Tatiane Tokushima, Rodrigo Antônio Carvalho Andraus   +5 more
doaj   +2 more sources

THE EXPRESSION OF TGF-1 AFTER LOW LEVEL LASER THERAPY IN INFLAMMATION ANIMAL MODEL

Folia Medica Indonesiana, 2017
Pain is the most common complaints in everyday practice. Pain is a clinical manifestation caused by stimuli due to potential tissue damage. Low level laser therapy (LLLT) has been used in reducing pain.
Imam Subadi, Indrayuni Lukitra Wardhani, Andriati Andriati   +2 more
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Comparative study between the effects of isolated manual therapy techniques and those associated with low level laser therapy on pain in patients with temporomandibular dysfunction [PDF]

, 2008
Objective: This study sought to evaluate the pain condition in patients with temporomandibular dysfunction after applying manual therapy techniques and those associated with this low level laser therapy.
Juliana Cristina Frare, Tarcila Nascimento Correa de Andrade   +1 more
core  

Towards Laser Driven Hadron Cancer Radiotherapy: A Review of Progress [PDF]

, 2014
It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with electron and ...
Bolton, P. R., Ledingham, K. W. D., Ma, C-M., Shikazono, N.   +3 more
core   +3 more sources

LOW LEVEL LASER THERAPY ON EXPERIMENTAL MYOPATHY

LASER THERAPY, 2011
The aim of the present work was to study the effect of Helium-Neon (HeNe) and Gallium Arsenide (GaAs) laser upon nitric oxide (NO) plasma levels, an inflammatory biomarker associated with oxidative stress, in rats with experimental myopathy. These were evaluated through histological assessment.The groups studied were: (A) control (intact rats that ...
Soledad, Dávila, María Belén, Vignola, David, Cremonezzi, Juan C, Simes, Fernando, Soriano, Vilma R, Campana   +5 more
openaire   +3 more sources