Results 51 to 60 of about 980 (213)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Non-linear Low-Light Image Enhancement Based on Fusion Color Model Space

open access: yes四川大学学报. 自然科学版, 2021
Lowlight images have problems such as low overall brightness of the image, uneven brightness, high color saturation, and image blur. To address these problems, a lowlight image enhancement algorithm fusing color model space is proposed, in which the ...
LIU Shou-Xin   +3 more
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

A Dual-Branch Autoencoder Network for Underwater Low-Light Polarized Image Enhancement

open access: yesRemote Sensing
Underwater detection faces uncomfortable illumination conditions, and traditional optical images sensitive to intensity often cannot work well in these conditions.
Chang Xue   +4 more
doaj   +1 more source

Low-Light Image Enhancement Method Based on Retinex Theory by Improving Illumination Map

open access: yesApplied Sciences, 2022
Recently, low-light image enhancement has attracted much attention. However, some problems still exist. For instance, sometimes dark regions are not fully improved, but bright regions near the light source or auxiliary light source are overexposed.
Xinxin Pan   +5 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Unsupervised Boosted Fusion Network for Single Low-Light Image Enhancement

open access: yesIEEE Access
Unsupervised methods are gradually becoming a research hotspot in low-light image enhancement due to their lack of paired training data and higher quality visual enhancement effects, but existing unsupervised low-light image enhancement methods generate ...
Jianfeng Zhang   +2 more
doaj   +1 more source

Low-Light Image Enhancement Based on Nonsubsampled Shearlet Transform

open access: yesIEEE Access, 2020
To improve the observability of low-light images, a low-light image enhancement algorithm based on nonsubsampled shearlet transform (NSST) is presented (LIEST). The proposed algorithm can synchronously achieve contrast improvement, noise suppression, and
Manli Wang   +4 more
doaj   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Home - About - Disclaimer - Privacy