Results 71 to 80 of about 157,053 (258)

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Unsupervised Boosted Fusion Network for Single Low-Light Image Enhancement

open access: yesIEEE Access
Unsupervised methods are gradually becoming a research hotspot in low-light image enhancement due to their lack of paired training data and higher quality visual enhancement effects, but existing unsupervised low-light image enhancement methods generate ...
Jianfeng Zhang   +2 more
doaj   +1 more source

Low-Light Image Enhancement Based on Nonsubsampled Shearlet Transform

open access: yesIEEE Access, 2020
To improve the observability of low-light images, a low-light image enhancement algorithm based on nonsubsampled shearlet transform (NSST) is presented (LIEST). The proposed algorithm can synchronously achieve contrast improvement, noise suppression, and
Manli Wang   +4 more
doaj   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Edge and Color Information Guided High-resolution Low-light Image Enhancement Algorithm [PDF]

open access: yesJisuanji kexue
The ability of the device to capture high-resolution images poses a new challenge to image processing,and most of the existing low-light image enhancement algorithms are designed for low-resolution images,and there are problems such as unclear details ...
ZHANG Ling, LI Zhenyu
doaj   +1 more source

Low-Light Image Enhancement Using Volume-Based Subspace Analysis

open access: yesIEEE Access, 2020
Low-light image enhancement is a key technique to overcome the quality degradation of photos taken under challenging illumination conditions. Even though the significant progress has been made for enhancing the poor visibility, the intrinsic noise ...
Wonjun Kim   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Extreme Low-Light Image Enhancement for Surveillance Cameras Using Attention U-Net

open access: yesSensors, 2020
Low-light image enhancement is one of the most challenging tasks in computer vision, and it is actively researched and used to solve various problems. Most of the time, image processing achieves significant performance under normal lighting conditions ...
Sophy Ai, Jangwoo Kwon
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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