Results 211 to 220 of about 1,179 (279)

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

Advanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi, Qian Tang, Sunren Sheng, Hongyi Jiang, Chen Jin, Chencheng Zhou, Chenglong Xie, Lin Zheng, Di Zhang, Hui Xu, Cong Xu, Haiwei Ma, Guangheng Xiang, Wenfei Ni, Xiaoyun Pan, Lei Yang, Huazi Xu, Yu Qian, Aimin Wu, Xiangyang Wang, Gang Zheng   +20 more
wiley   +1 more source

Natural Toolbox–Chemical Engineering Aspect and High‐Value Applications of Janus Cellulose Nanomaterials

Advanced Science, EarlyView.
The Tai Ji symbol from China represents the co‐existence of two opposite substances, similar to quantum entanglement. The term Janus comes from ancient Roman religion and mythology. Janus, the god of beginnings, transitions, etc., has two faces, symbolizing duality. Janus cellulose nanomaterials show structural duality.
Yu Zhao, Shengjie Wang, Zongchen Wei, Shiming Qiu, Guofu Zhou, Jr‐Hau He, Xuezhu Xu   +6 more
wiley   +1 more source

A luminous and young galaxy at z = 12.33 revealed by a JWST/MIRI detection of Hα and [O iii]. [PDF]

Nat Astron
Zavala JA, Castellano M, Akins HB, Bakx TJLC, Burgarella D, Casey CM, Chávez Ortiz ÓA, Dickinson M, Finkelstein SL, Mitsuhashi I, Nakajima K, Pérez-González PG, Arrabal Haro P, Bergamini P, Buat V, Backhaus B, Calabrò A, Cleri NJ, Fernández-Arenas D, Fontana A, Franco M, Grillo C, Giavalisco M, Grogin NA, Hathi N, Hirschmann M, Ikeda R, Jung I, Kartaltepe JS, Koekemoer AM, Larson RL, McKinney J, Papovich C, Rosati P, Saito T, Santini P, Terlevich R, Terlevich E, Treu T, Yung LYA.   +39 more
europepmc   +1 more source

Pushing the Frontiers: Artificial Intelligence (AI)‐Guided Programmable Concepts in Binary Self‐Assembly of Colloidal Nanoparticles

Advanced Science, EarlyView.
Colloidal nanoparticles self‐assembly advances towards intelligent, customized assembly through precise control of binary co‐assemblies. This review explores the evolution from monolithic to binary assemblies, highlighting how the AI‐guided programmable assembly approach has the potential to shift from passive assembly to active intelligent design.
Cancan Li, Lindong Ma, Zhenjie Xue, Xiao Li, Shan Zhu, Tie Wang   +5 more
wiley   +1 more source

Strong Lensing by Galaxies. [PDF]

Space Sci Rev
Shajib AJ, Vernardos G, Collett TE, Motta V, Sluse D, Williams LLR, Saha P, Birrer S, Spiniello C, Treu T.   +9 more
europepmc   +1 more source

Real‐Time Probing of Morphological Evolution and Recrystallization During Solvent Annealing in Blade‐Coated All‐Polymer Organic Solar Cells Using In Situ X‐Ray Scattering

Advanced Science, EarlyView.
In situ grazing‐incidence X‐ray scattering and in situ UV–vis spectroscopy are being used for the first time to reveal the morphological evolution of all‐polymer solar cell (APSCs) blends during solvent vapor annealing (SVA). SVA strongly influences the recrystallization and reordering behavior of APSCs blends, successfully establishing the ...
Jialiang Hao, Yang Feng, Qianyi Ma, Hongxiang Li, Chunxia Hong, Chen Hou, Ying Wang, Yang Jing, Yiwen Li, Guangfeng Liu, Xiuhong Li, Aiguo Li, Fenggang Bian, Ruijie Ma, Yuanyang Wang, Yuying Huang, Chunming Yang   +16 more
wiley   +1 more source

Impact of Noncompensating Ions on the Electrochemical Performance of n-Type Polymeric Mixed Conductors. [PDF]

J Am Chem Soc
Ohayon D, Hamidi-Sakr A, Surgailis J, Wustoni S, Dereli B, Wehbe N, Nastase S, Chen X, McCulloch I, Cavallo L, Inal S.   +10 more
europepmc   +1 more source

MoS2 Channel‐Enhanced High‐Density Charge Trap Flash Memory and Machine Learning‐Assisted Sensing Methodologies for Memory‐Centric Computing Systems

Advanced Science, EarlyView.
Driven by AI computing demands, this study investigates MoS2 channels for 3D NAND Flash to achieve high‐density, low‐power, and reliable nonvolatile memory. MoS2 enables a large memory window and lower operating voltages with low‐k tunneling layer, demonstrating endurance of 10⁴ cycles and retention of 10⁵ s. Comprehensive analyses and machine learning‐
Ki Han Kim, Ju Han Park, Khang June Lee, Ji‐Won Seo, Yeong Kwon Kim, Junhwan Choi, Min‐Jae Seo, Byung Chul Jang   +7 more
wiley   +1 more source

Fast pH‐Driven Solubilization Method of Realgar (As4S4) to Reduce the Toxicity of Arsenic [As(III)] for Medicinal Purposes

Advanced Science, EarlyView.
Arsenic trioxide transformed acute promyelocytic leukemia therapy and shows promise against HIV. A new method to solubilize the mineral realgar produces different arsenic species depleting the main arsenic target, nuclear PML protein, and retaining effects on leukemic and HIV reservoir cells, while minimizing off‐target damage.
Bojana Lucic, Douglas Santana Franciscato, Helton Pereira Nogueira, Lara Gallucci, Alceu Totti Silveira Junior, Asmaa Mohamed Ismail, Millie Robinson, Teresa Dallinger, Claudia Gutfleisch, Jochen Kurz, Maytê Toledo, Jessica Dias da Silva Ferraz, Mohammad Tarek, Danilo Dias, Ricardo Sobhie Diaz, Mahmoud ElHefnawi, Mattia Forcato, Hugo P Monteiro, Marina Lusic, Iart Luca Shytaj, Andrea Savarino   +20 more
wiley   +1 more source

Towards an adequate description of the dose-response relationship in BNCT of glioblastoma multiforme. [PDF]

Med Phys
Marcaccio B, Crepaldi M, Postuma I, Simeone E, Guidi C, Fatemi S, Ramos RL, Vercesi V, Ferrari C, Cansolino L, Delgrosso E, Liberto RD, Dondi D, Vadivel D, Chen YW, Chou FI, Peir JJ, Wu CJ, Tsai HY, Lee JC, Portu AM, Viegas AMD, González SJ, Bortolussi S.   +23 more
europepmc   +1 more source