Results 211 to 220 of about 17,679,315 (300)

PrOMet: Accurate and Robust Metal‐Binding Site and Type Prediction

Advanced Science, EarlyView.
PrOMet is a two‐stage deep learning framework for jointly predicting metal‐binding sites and ion identities from protein structures. Surface candidate sites are first pruned, followed by refinement of the most probable sites and metal types. This hierarchical strategy enables robust and accurate metal prediction for cryo‐EM and AlphaFold‐derived ...
Gangeun Park, Chaok Seok, Hahnbeom Park
wiley   +1 more source

Sarbecoviruses Suppress Innate Immunity by Recruiting PPM1A to Modulate STAT2 and ORF9b Phosphorylation

Advanced Science, EarlyView.
Sarbecovirus ORF9b recruits host phosphatase PPM1A to suppress innate immunity through dual mechanisms. PPM1A directly dephosphorylates ORF9b to sustain its activity and indirectly downregulates STAT2 phosphorylation to impair interferon signaling. Pharmacological inhibition of PPM1A restores antiviral responses and limits sarbecovirus replication ...
Lixiang Xie, Ziye Huang, Zhiyuan Zhang, Yiqiang Zhu, Xiaoqing Liu, Lei Wang, Tongyu Bi, Taizhen Liang, Jintao Lai, Meilin Hu, Guochang Qiu, Shiqi Xiao, Sen Liu, Yaoming Liu, Haiyue Rao, Tao Chen, Haojie Peng, Bin Zhang, Jia Tang, Qianying Li, Yaxin Li, Yuxin Hou, Weibo Yang, Hewei Jiang, Xiancai Ma   +24 more
wiley   +1 more source

Dual Randomness From Spatial and Temporal Variations in Stochastic Zinc Gallate Nanoclusters for PUF and TRNG Co‐Driven Image Generation

Advanced Science, EarlyView.
A dual‐randomness hardware platform is demonstrated by integrating PUF and TRNG functionalities into mixed‐ZGO nanoclusters. By leveraging spatial and temporal stochasticity, the mixed‐ZGO NCs device enables both unique identification and random signal generation.
Seungme Kang, Wangmyung Choi, Jueun Lee, Yeong Kwon Kim, Byung Chul Jang, Wonjun Shin, Hocheon Yoo   +6 more
wiley   +1 more source

Synergistic Mechano‐Fluidic Self‐Fusion of Poly(Vinyl Alcohol)‐Modified Liquid‐Metal Particles for Post‐Treatment‐Free Soft Electronics

Advanced Science, EarlyView.
Poly(vinyl alcohol)‐modified liquid‐metal particles form conductive networks through spray‐induced self‐fusion without additional post‐treatment. Spray impact initiates oxide‐shell rupture and electrical contact, while subsequent Marangoni flow and capillary forces promote particle redistribution, neck growth, and network consolidation. This sequential
Keun‐Young Yook, Sangwon Kim, Chansoo Kim, Minkyong Kang, Yurim Lee, Mido Kim, Kijun Park, Seung Yeop Han, Seung‐Woo Cho, Gun‐Hee Lee, Kayoung Son, Hanbit Jang, Tae Young Kim, Jungmok Seo   +13 more
wiley   +1 more source

Scalable Fabrication of MOF Glass Membranes for Gas Separation via Stepwise Phase Transition

Advanced Science, EarlyView.
Metal‐organic framework (MOF) glass membranes, with their excellent processability and permanent pore structure, have great potential for gas separation applications. However, during large‐scale fabrication, defects and obvious cracks are prone to occur due to the limitations of powder processing.
Mao Ye, Yi Yang, Zibo Yang, Yuxiu Sun, De Ao, Fan Zhou, Ying Chen, Chunhui Luo, Ziyao Wang, Wenjia Sun, Yunling Jia, Wengang Huang, Jingwei Hou, Zhi Wang, Zhihua Qiao   +14 more
wiley   +1 more source

Revealing Temperature‐Driven Interfacial Reactions of Succinonitrile in PEO‒LiTFSI Electrolytes and Suppressing Them via Dual PEDOT‐Based Interfacial Layers

Advanced Science, EarlyView.
Temperature‐driven interfacial reactions of succinonitrile in PEO‐LiTFSI electrolyte are revealed at both lithium and cathode interfaces, identifying cathode degradation as the dominant failure pathway. Dual PEDOT‐based interfacial protection suppresses these reactions, stabilizes both electrode interfaces, and enables durable wide‐temperature solid ...
Baskar Selvaraj, Hailemichael Ayalew, Yu‐Yao Tsai, Ly Tho Xuan, Jia‐Wei She, Hao‐Wen Liu, Ming‐Chou Chen, Yu‐Sheng Hsiao, Nae‐Lih Wu, Hsiao‐hua Yu   +9 more
wiley   +1 more source

Nanoscale Buried Interface Control in Silicone Hydrogels Enables a Biointerface Engineering Platform

Advanced Science, EarlyView.
A hydrophilic coating with controllable nanoscale thickness is applied to commercial silicone hydrogel contact lenses. By combining comprehensive multi‐modal three‐dimensional characterization with an advanced algorithm, the thickness and chemical information of these multilayered structures are resolved.
Po‐Hsiang Chen, Jia‐Hua Wang, Ching Chen, Shih‐Hsuan Fu, Rajan Deepan Chakravarthy, Hsin‐Chieh Lin   +5 more
wiley   +1 more source

The faintest, extremely variable X-ray tidal disruption event from a supermassive black hole binary? [PDF]

Innovation (Camb)
Huang M, Xue Y, Li S, Liu F, Zhu S, Chen JH, Shen RF, Wang Y, Yang Y, Jiang N, Bauer FE, Vignali C, Zou F, Wang J, Filippenko AV, Luo B, Qin C, Quirola-Vásquez J, Wang JX, Fan L, Sun M, Wu Q, Ni Q, Brink TG, Wang T, Zheng W, Shu X, Zheng X, Lin X, Kong X, Wang Y, Luo Y, Lin Z.   +32 more
europepmc   +1 more source

Accretion flows and neutron star heating in low-mass X-ray binaries

, 2017
X-ray binaries are excellent test beds for studies of high-energy accretion flows and the properties of compact objects. Neutron star (NS) low-mass X-ray binaries (LMXBs) vary in brightness by almost 8 orders of magnitude and are hosts to diverse accretion flows, transporting varying amounts of energy and mass toward the central NS, as well as ...
openaire   +1 more source

A Hypothalamic Oxytocinergic–Sympathetic Axis Couples Anxiety Dysregulation With Impaired Tendon–Bone Repair

Advanced Science, EarlyView.
RCI is associated with functional suppression of oxytocinergic neurons in the PVN. Reduced PVNOXT neuronal activity contributes to altered sympathetic regulation involving the IML–sympathetic chain pathway, accompanied by changes in norepinephrine signaling at the BTI.
Liyang Wan, Tingmo Huang, Liyue Zeng, Ruixue Du, Hengshuo Zhang, Shen Liu, Tao Zhang, Jianzhong Hu, Hongbin Lu   +8 more
wiley   +1 more source