Results 81 to 90 of about 2,428,196 (357)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Low power arcjet performance [PDF]

open access: yes
An experimental investigation was performed to evaluate arc jet operation at low power. A standard, 1 kW, constricted arc jet was run using nozzles with three different constrictor diameters.
Curran, Francis M.   +1 more
core   +1 more source

Low Power Resonant Optical Excitation of an Optomechanical Cavity

open access: yes, 2010
We demonstrate the actuation of a double beam opto-mechanical cavity with a sinusoidally varying optical input power. We observe the driven mechanical motion with only 200 nW coupled to the optical cavity mode.
Altug   +23 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Low Power system Design techniques for mobile computers [PDF]

open access: yes, 1997
Portable products are being used increasingly. Because these systems are battery powered, reducing power consumption is vital. In this report we give the properties of low power design and techniques to exploit them on the architecture of the system.
Havinga, Paul J.M., Smit, Gerard J.M.
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Whisper: Fast Flooding for Low-Power Wireless Networks

open access: yes, 2018
This paper presents Whisper, a fast and reliable protocol to flood small amounts of data into a multi-hop network. Whisper relies on three main cornerstones.
Brachmann, Martina   +3 more
core   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

A Study on the Evolution of Flow Regime in a Gas-Assisted Submerged High-Pressure Water Jet

open access: yesFluids
High-pressure water jet technology is widely utilized for cleaning marine artificial structures due to its portability, efficiency, and environmental friendliness, yet traditional jets underperform in submerged environments.
Hao Yan   +3 more
doaj   +1 more source

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