Results 201 to 210 of about 26,664 (234)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

Advanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat, Johan Sebastian Lopez‐Parra, Willem M. H. Hoogaars, Emma Dijkstra, Cynthia Huang, Irafasha C. Casmil, Anna K. Blakney, Peter Olinga, Barbara Rothen‐Rutishauser, Hélder A. Santos, Alke Petri‐Fink, Flávia Sousa   +11 more
wiley   +1 more source

From Clinic to Computation: Multiscale Bioengineering Strategies for Durable Biological Aortic Valve Replacements

Advanced Functional Materials, EarlyView.
Bioprosthetic aortic valves have revolutionized the treatment of aortic stenosis, but their durability is limited by structural valve deterioration (SVD). This review focuses on the pericardial tissue at the heart of these valves, examining how its mechanical properties and calcification drive fatigue and failure.
Gabriele Greco, Pierfrancesco Gaziano, Serena Anglese, Simone Morganti, Carlo de Vincentiis, Ferdinando Auricchio, Michele Marino, Michele Conti   +7 more
wiley   +1 more source

AI-Driven Drug Discovery: A Comprehensive Review. [PDF]

ACS Omega
Ferreira FJN, Carneiro AS.
europepmc   +1 more source

Anomalous Pressure‐Temperature Ultrahigh Sensitivities in Atomically Engineered Carbonitride MXenes for Multifunctional Wearable Human–Machine Interfaces: Joint Computational–Experimental Elucidations

Advanced Functional Materials, EarlyView.
Atomically engineered layered 2D Ti3CNTz carbonitride MXene exhibits ultrahigh heat and pressure sensitivity, enabling dual‐mode sensors with 300%–400% performance enhancement and durability for real‐time health‐monitoring interface devices. Precise nitrogen incorporation (e.g., Ti3C1.8N0.2Tz) boosts conductivity, enhancing temperature response, while ...
Debananda Mohapatra, Ju‐Hyoung Han, Hyun Jin Kang, Jeong Eun Byun, Seonghun Lee, Sanghyuk Lee, Yeseul Son, Jaeeun Park, Tae Joo Shin, Youngho Kang, Jung Woo Lee, Soon‐Yong Kwon, Soo‐Hyun Kim   +12 more
wiley   +1 more source

Study on the Charge Characteristics and Migration Characteristics of Amorphous Alloy Core Debris. [PDF]

Materials (Basel)
Yu W, Guan X.
europepmc   +1 more source

DNA framework-based molecular transformer for logic-driven precision diagnostics. [PDF]

Sci Adv
Zhang S, Xia K, Wang L, Fan C, Yin F, Zuo X.   +5 more
europepmc   +1 more source

The TRACERS Analyzer for Cusp Electrons. [PDF]

Space Sci Rev
Halekas JS, Hansen C, Ruhunusiri S, Sheets D, Washington A, Beals RM, Bounds SR, Carton A, Christopher IW, Crawford D, Deasy K, Dolan JS, Dvorsky R, Feltman C, Hinson G, Hisel S, Lasko A, Moore A, Morris K, Piker CW, Steele K, Wilkinson D, Kletzing CA, Miles DM.   +23 more
europepmc   +1 more source

Lightweight convolutional neural network for real-time earthquake P-wave detection on edge devices in New Zealand. [PDF]

Sci Rep
Ravishan D, Prasanna R, Herath P, Doyle EEH.   +3 more
europepmc   +1 more source

Multimodal AI for Real-Time Food Safety and Quality: From Sensors to Foundation Models, Edge Deployment, and Regulation. [PDF]

Food Sci Nutr
Chen Z, Zhang G, Zhang F.
europepmc   +1 more source

A capacitive-piezoelectric hybrid MEMS microphone with signal fusion for enhancing signal-to-noise ratio. [PDF]

Microsyst Nanoeng
Guan Y, Schneider M, Li D, Zhang H, Mi J, Bertrand A, Sadeghpour S, Wang C, Liu H, Glorieux C, Kraft M.   +10 more
europepmc   +1 more source